Literature DB >> 12845393

Methylene blue.

Jack Clifton1, Jerrold B Leikin.   

Abstract

Methylene blue finds its major utilization in toxicology in the treatment of methemoglobinemia at a dose of 1 to 2 mg/kg intravenously. By interacting with methemoglobin and the erythrocyte's enzyme systems to reduce back to hemoglobin, methylene blue is a generally safe drug with dose-related hemolytic effects. People with G-6-PD deficiency, along with patients exposed to aniline dyes and dapsone, may present with special risks in the treatment of methemoglobinemia.

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Year:  2003        PMID： 12845393     DOI： 10.1097/00045391-200307000-00009

Source DB:  PubMed          Journal:  Am J Ther        ISSN： 1075-2765            Impact factor:   2.688


  75 in total

1.  Baseline in vitro activities of the antimalarials pyronaridine and methylene blue against Plasmodium falciparum isolates from Kenya.

Authors:  John Okombo; Steven M Kiara; Leah Mwai; Lewa Pole; Eric Ohuma; Lynette Isabella Ochola; Alexis Nzila
Journal:  Antimicrob Agents Chemother       Date:  2011-11-28       Impact factor: 5.191

2.  Methylene blue modulates β-secretase, reverses cerebral amyloidosis, and improves cognition in transgenic mice.

Authors:  Takashi Mori; Naoki Koyama; Tatsuya Segawa; Masahiro Maeda; Nobuhiro Maruyama; Noriaki Kinoshita; Huayan Hou; Jun Tan; Terrence Town
Journal:  J Biol Chem       Date:  2014-08-25       Impact factor: 5.157

Review 3.  Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue.

Authors:  Julio C Rojas; Aleksandra K Bruchey; F Gonzalez-Lima
Journal:  Prog Neurobiol       Date:  2011-11-03       Impact factor: 11.685

4.  Effects of nitric oxide inhibition by methylene blue in cirrhotic patients with ascites.

Authors:  Georgios Kalambokis; Michalis Economou; Andreas Fotopoulos; Jihad Al Bokharhii; Pappas Christos; Kosta Paraskevi; Papadimitriou Konstantinos; Afroditi Katsaraki; Epameinondas V Tsianos
Journal:  Dig Dis Sci       Date:  2005-10       Impact factor: 3.199

5.  Phenothiazinium antimicrobial photosensitizers are substrates of bacterial multidrug resistance pumps.

Authors:  George P Tegos; Michael R Hamblin
Journal:  Antimicrob Agents Chemother       Date:  2006-01       Impact factor: 5.191

6.  Multimodal Randomized Functional MR Imaging of the Effects of Methylene Blue in the Human Brain.

Authors:  Pavel Rodriguez; Wei Zhou; Douglas W Barrett; Wilson Altmeyer; Juan E Gutierrez; Jinqi Li; Jack L Lancaster; Francisco Gonzalez-Lima; Timothy Q Duong
Journal:  Radiology       Date:  2016-06-28       Impact factor: 11.105

7.  Nodal lymph flow quantified with afferent vessel input function allows differentiation between normal and cancer-bearing nodes.

Authors:  Alisha V DSouza; Jonathan T Elliott; Jason R Gunn; Richard J Barth; Kimberley S Samkoe; Kenneth M Tichauer; Brian W Pogue
Journal:  Biomed Opt Express       Date:  2015-03-17       Impact factor: 3.732

Review 8.  Can microbial cells develop resistance to oxidative stress in antimicrobial photodynamic inactivation?

Authors:  Nasim Kashef; Michael R Hamblin
Journal:  Drug Resist Updat       Date:  2017-07-26       Impact factor: 18.500

9.  A Mechanistic Investigation of Methylene Blue and Heparin Interactions and Their Photoacoustic Enhancement.

Authors:  Junxin Wang; Ananthakrishnan Soundaram Jeevarathinam; Kathryn Humphries; Anamik Jhunjhunwala; Fang Chen; Ali Hariri; Bill R Miller; Jesse V Jokerst
Journal:  Bioconjug Chem       Date:  2018-10-16       Impact factor: 4.774

10.  A severe case of vasoplegic shock following metformin overdose successfully treated with methylene blue as a last line therapy.

Authors:  Rachel Erin Graham; Michaela Cartner; James Winearls
Journal:  BMJ Case Rep       Date:  2015-07-06
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