Literature DB >> 12822185

Antimycobacterial activity of 1-substituted indolizines.

Lise-Lotte Gundersen1, Ayele H Negussie, Frode Rise, Ole Benny ØStby.   

Abstract

Indolizine derivatives were tested as antimycobacterials against Mycobacterium tuberculosis H(37)Rv (ATCC 27294)in BACTEC 12B medium using the Microplate Alamar Blue Assay. The most active compounds examined carry an alpha-hydroxybenzyl substituent in the indolizine 1-position. MICs against Mycobacterium tuberculosis for these compounds were 6.25 microg/mL

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Year:  2003        PMID： 12822185     DOI： 10.1002/ardp.200390019

Source DB:  PubMed          Journal:  Arch Pharm (Weinheim)        ISSN： 0365-6233            Impact factor:   3.751


  6 in total

1.  One-pot synthesis of highly substituted N-fused heteroaromatic bicycles from azole aldehydes.

Authors:  Victor K Outlaw; Felipe B d'Andrea; Craig A Townsend
Journal:  Org Lett       Date:  2015-03-27       Impact factor: 6.005

2.  Silver-Mediated Synthesis of Indolizines via Oxidative C-H functionalization and 5- endo-dig cyclization.

Authors:  Amit N Pandya; James T Fletcher; Eric M Villa; Devendra K Agrawal
Journal:  Tetrahedron Lett       Date:  2014-12-10       Impact factor: 2.415

3.  (8aS)-7,8,8a,9-Tetra-hydro-thieno[3,2-f]indolizin-6(4H)-one.

Authors:  Lubomír Svorc; Viktor Vrábel; Jozef Kožíšek; Stefan Marchalín; Peter Safář
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-03-06

4.  Methyl 9-(4-bromo-phen-yl)-8a,9,9a,10,11,12,13,14a-octa-hydro-8H-benzo[f]chromeno[3,4-b]indolizine-8a-car-box-ylate.

Authors:  B Gunasekaran; S Kathiravan; R Raghunathan; G Chakkaravarthi; V Manivannan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-09-26

5.  (7R,8R,8aS)-8-Hydr-oxy-7-phenyl-per-hydro-indolizin-3-one.

Authors:  Lubomír Svorc; Viktor Vrábel; Jozefína Zúžiová; Mária Bobošíková; Jozef Kožíšek
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-03-28

6.  An improved synthesis of some 5-substituted indolizines using regiospecific lithiation.

Authors:  Alexey G Kuznetsov; Alexander A Bush; Viktor B Rybakov; Eugene V Babaev
Journal:  Molecules       Date:  2005-09-30       Impact factor: 4.411
  6 in total

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