Literature DB >> 12821488

Ribosomal mutations conferring resistance to macrolides in Streptococcus pneumoniae clinical strains isolated in Germany.

Ralf René Reinert1, Angela Wild, Peter Appelbaum, Rudolf Lütticken, Murat Yücel Cil, Adnan Al-Lahham.   

Abstract

Among a collection of 4281 pneumococcal isolates, 7 strains isolated in Germany had an unusual macrolide resistance phenotype. The isolates were found to have multiple mutations in the 23S rRNA and alterations in the L4 ribosomal protein. One strain had an amino acid alteration in the L22 ribosomal protein.

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Year:  2003        PMID： 12821488      PMCID： PMC161879          DOI： 10.1128/AAC.47.7.2319-2322.2003

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  23 in total

1.  Mutation in 23S rRNA responsible for resistance to 16-membered macrolides and streptogramins in Streptococcus pneumoniae.

Authors:  F Depardieu; P Courvalin
Journal:  Antimicrob Agents Chemother       Date:  2001-01       Impact factor: 5.191

2.  Emergence of macrolide resistance during treatment of pneumococcal pneumonia.

Authors:  Daniel M Musher; Mark E Dowell; Virginia D Shortridge; Robert K Flamm; James H Jorgensen; Pierre Le Magueres; Kurt L Krause
Journal:  N Engl J Med       Date:  2002-02-21       Impact factor: 91.245

3.  Resistance to macrolides and related antibiotics in Streptococcus pneumoniae.

Authors:  Roland Leclercq; Patrice Courvalin
Journal:  Antimicrob Agents Chemother       Date:  2002-09       Impact factor: 5.191

4.  Diversity of ribosomal mutations conferring resistance to macrolides, clindamycin, streptogramin, and telithromycin in Streptococcus pneumoniae.

Authors:  Annie Canu; Brigitte Malbruny; Maëlle Coquemont; Todd A Davies; Peter C Appelbaum; Roland Leclercq
Journal:  Antimicrob Agents Chemother       Date:  2002-01       Impact factor: 5.191

5.  Emergence of macrolide and penicillin resistance among invasive pneumococcal isolates in Germany.

Authors:  Ralf René Reinert; Adnan Al-Lahham; Maria Lemperle; Christoph Tenholte; Claudia Briefs; Stefan Haupts; Hans Hubert Gerards; Rudolf Lütticken
Journal:  J Antimicrob Chemother       Date:  2002-01       Impact factor: 5.790

6.  Macrolide resistance among invasive Streptococcus pneumoniae isolates.

Authors:  T B Hyde; K Gay; D S Stephens; D J Vugia; M Pass; S Johnson; N L Barrett; W Schaffner; P R Cieslak; P S Maupin; E R Zell; J H Jorgensen; R R Facklam; C G Whitney
Journal:  JAMA       Date:  2001-10-17       Impact factor: 56.272

7.  Susceptibilities to telithromycin and six other agents and prevalence of macrolide resistance due to L4 ribosomal protein mutation among 992 Pneumococci from 10 central and Eastern European countries.

Authors:  Kensuke Nagai; Peter C Appelbaum; Todd A Davies; Linda M Kelly; Dianne B Hoellman; Arjana Tambic Andrasevic; Liga Drukalska; Waleria Hryniewicz; Michael R Jacobs; Jana Kolman; Jolanta Miciuleviciene; Marina Pana; Lena Setchanova; Marianne Konkoly Thege; Helena Hupkova; Jan Trupl; Pavla Urbaskova
Journal:  Antimicrob Agents Chemother       Date:  2002-02       Impact factor: 5.191

8.  Ribosomal mutations in Streptococcus pneumoniae clinical isolates.

Authors:  Marja Pihlajamäki; Janne Kataja; Helena Seppälä; John Elliot; Maija Leinonen; Pentti Huovinen; Jari Jalava
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

9.  Identification of an erm(A) erythromycin resistance methylase gene in Streptococcus pneumoniae isolated in Greece.

Authors:  G A Syrogiannopoulos; I N Grivea; A Tait-Kamradt; G D Katopodis; N G Beratis; J Sutcliffe; P C Appelbaum; T A Davies
Journal:  Antimicrob Agents Chemother       Date:  2001-01       Impact factor: 5.191

Review 10.  Will resistance to ketolides develop in Streptococcus pneumoniae?

Authors:  R Leclercq
Journal:  J Infect       Date:  2002-02       Impact factor: 6.072
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  20 in total

1.  High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae.

Authors:  Nicole Wolter; Anthony M Smith; Donald E Low; Keith P Klugman
Journal:  Antimicrob Agents Chemother       Date:  2007-01-08       Impact factor: 5.191

2.  Telithromycin-nonsusceptible clinical isolates of Streptococcus pneumoniae from Europe.

Authors:  Adnan Al-Lahham; Peter C Appelbaum; Mark van der Linden; Ralf René Reinert
Journal:  Antimicrob Agents Chemother       Date:  2006-11       Impact factor: 5.191

3.  In vitro activities of novel 2-fluoro-naphthyridine-containing ketolides.

Authors:  Darren Abbanat; Glenda Webb; Barbara Foleno; Y Li; Mark Macielag; Deborah Montenegro; Ellyn Wira; Karen Bush
Journal:  Antimicrob Agents Chemother       Date:  2005-01       Impact factor: 5.191

4.  Macrolide efflux in Streptococcus pneumoniae is mediated by a dual efflux pump (mel and mef) and is erythromycin inducible.

Authors:  Karita D Ambrose; Rebecca Nisbet; David S Stephens
Journal:  Antimicrob Agents Chemother       Date:  2005-10       Impact factor: 5.191

5.  Molecular characterization of the first telithromycin-resistant Streptococcus pneumoniae isolate in Germany.

Authors:  Ralf René Reinert; Mark van der Linden; Adnan Al-Lahham
Journal:  Antimicrob Agents Chemother       Date:  2005-08       Impact factor: 5.191

Review 6.  Ketolides--the modern relatives of macrolides : the pharmacokinetic perspective.

Authors:  Markus Zeitlinger; Claudia Christina Wagner; Birgit Heinisch
Journal:  Clin Pharmacokinet       Date:  2009       Impact factor: 6.447

Review 7.  Multidrug-resistant Streptococcus pneumoniae infections: current and future therapeutic options.

Authors:  Françoise Van Bambeke; René R Reinert; Peter C Appelbaum; Paul M Tulkens; Willy E Peetermans
Journal:  Drugs       Date:  2007       Impact factor: 9.546

8.  Molecular epidemiology of macrolide-resistant Streptococcus pneumoniae isolates in Europe.

Authors:  Ralf René Reinert; Adrian Ringelstein; Mark van der Linden; Murat Yücel Cil; Adnan Al-Lahham; Franz-Josef Schmitz
Journal:  J Clin Microbiol       Date:  2005-03       Impact factor: 5.948

9.  High prevalence of the ermB gene among erythromycin-resistant streptococcus pneumoniae isolates in Germany during the winter of 2000-2001 and in vitro activity of telithromycin.

Authors:  Michael Kresken; Beate Henrichfreise; Simone Bagel; Johannes Brauers; Bernd Wiedemann
Journal:  Antimicrob Agents Chemother       Date:  2004-08       Impact factor: 5.191

Review 10.  Antimicrobial treatment guidelines for acute bacterial rhinosinusitis.

Authors:  Jack B Anon; Michael R Jacobs; Michael D Poole; Paul G Ambrose; Mark S Benninger; James A Hadley; William A Craig
Journal:  Otolaryngol Head Neck Surg       Date:  2004-01       Impact factor: 3.497
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