Literature DB >> 12796442

Defining death in non-heart beating organ donors.

N Zamperetti1, R Bellomo, C Ronco.   

Abstract

Protocols for retrieving vital organs in consenting patients in cardiovascular arrest (non-heart beating donors, NHBD) rest on the assumptions that irreversible asystole a) identifies the instant of biological death, and b) is clinically assessable at the time when retrieval of vital organs is possible. Unfortunately both assumptions are flawed. We argue that traditional life/death definitions could be actually inadequate to represent the reality of dying under intensive support, and we suggest redefining NHBD protocols on moral, social, and anthropological criteria, admitting that irreversible (however defined) asystole can only equate a clinically determinable point of no return in the process of dying, where organ retrieval can be morally and socially accepted in previously consenting patients.

Entities:  

Keywords:  Death and Euthanasia; Health Care and Public Health

Mesh:

Year:  2003        PMID: 12796442      PMCID: PMC1733717          DOI: 10.1136/jme.29.3.182

Source DB:  PubMed          Journal:  J Med Ethics        ISSN: 0306-6800            Impact factor:   2.903


  31 in total

1.  When is "dead"?

Authors:  S J Youngner; R M Arnold; M A DeVita
Journal:  Hastings Cent Rep       Date:  1999 Nov-Dec       Impact factor: 2.683

2.  The diagnosis of brain death.

Authors:  M J Broyde
Journal:  N Engl J Med       Date:  2001-08-23       Impact factor: 91.245

3.  The brain and somatic integration: insights into the standard biological rationale for equating "brain death" with death.

Authors:  A D Shewmon
Journal:  J Med Philos       Date:  2001-10

4.  Recovery from "brain death": a neurologist's apologia.

Authors:  D Alan Shewmon
Journal:  Linacre Q       Date:  1997-02

5.  The Institute of Medicine's report on non-heart-beating organ transplantation.

Authors:  Roger Herdman; Tom L Beauchamp; John T Potts
Journal:  Kennedy Inst Ethics J       Date:  1998-03

6.  Non-heart-beating organ donation: a defense of the required determination of death.

Authors:  James DuBois
Journal:  J Law Med Ethics       Date:  1999       Impact factor: 1.718

7.  Doubts about death: the silence of the Institute of Medicine.

Authors:  Jerry Menikoff
Journal:  J Law Med Ethics       Date:  1998       Impact factor: 1.718

8.  The new definition of death. Some opposing views.

Authors:  H K Beecher; H I Dorr
Journal:  Int Z Klin Pharmakol Ther Toxikol       Date:  1971-10

9.  Death following spontaneous recovery from cardiopulmonary arrest in a hospital mortuary: 'Lazarus phenomenon' in a case of alleged medical negligence.

Authors:  Hitoshi Maeda; Masaki Q Fujita; Bao-Li Zhu; Hidekazu Yukioka; Mitsuo Shindo; Li Quan; Kaori Ishida
Journal:  Forensic Sci Int       Date:  2002-06-25       Impact factor: 2.395

Review 10.  Unexpected return of spontaneous circulation after cessation of resuscitation (Lazarus phenomenon)

Authors:  W H Maleck; S N Piper; J Triem; J Boldt; F U Zittel
Journal:  Resuscitation       Date:  1998 Oct-Nov       Impact factor: 5.262

View more
  9 in total

1.  Cardiac death or circulatory arrest? Facts and values in organ retrieval after diagnosis of death by cardio-circulatory criteria.

Authors:  Nereo Zamperetti; Rinaldo Bellomo; Claudio Ronco
Journal:  Intensive Care Med       Date:  2009-07-10       Impact factor: 17.440

2.  Neurointensivists' opinions about death by neurological criteria and organ donation.

Authors:  Adrienne R Boissy; J Javier Provencio; Cheryl A Smith; Michael N Diringer
Journal:  Neurocrit Care       Date:  2005       Impact factor: 3.210

Review 3.  Individual choice in the definition of death.

Authors:  A Bagheri
Journal:  J Med Ethics       Date:  2007-03       Impact factor: 2.903

4.  A Comparison of Request Process and Outcomes in Donation After Cardiac Death and Donation After Brain Death: Results From a National Study.

Authors:  L A Siminoff; G P Alolod; M Wilson-Genderson; E Y N Yuen; H M Traino
Journal:  Am J Transplant       Date:  2016-11-21       Impact factor: 8.086

5.  In defense of the reverence of all life: Heideggerean dissolution of the ethical challenges of organ donation after circulatory determination of death.

Authors:  D J Isch
Journal:  Med Health Care Philos       Date:  2007-05-02

6.  Donation after cardiac death: a survey of university student opinions on death and donation.

Authors:  Ari R Joffe; Roisin Byrne; Natalie R Anton; Allan R deCaen
Journal:  Intensive Care Med       Date:  2008-08-01       Impact factor: 17.440

Review 7.  Irreversible apnoeic coma 35 years later. Towards a more rigorous definition of brain death?

Authors:  Nereo Zamperetti; Rinaldo Bellomo; Carlo Alberto Defanti; Nicola Latronico
Journal:  Intensive Care Med       Date:  2004-01-14       Impact factor: 17.440

8.  Brain-dead patients are not cadavers: the need to revise the definition of death in Muslim communities.

Authors:  Mohamed Y Rady; Joseph L Verheijde
Journal:  HEC Forum       Date:  2013-03

9.  Defining the vital condition for organ donation.

Authors:  Rinaldo Bellomo; Nereo Zamperetti
Journal:  Philos Ethics Humanit Med       Date:  2007-11-19       Impact factor: 2.464

  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.