| Literature DB >> 12760887 |
Daiva Bakonyte1, Aurelija Baranauskaite, Jurate Cicenaite, Anaida Sosnovskaja, Petras Stakenas.
Abstract
Mutations at codon 315 of the katG gene were detected in 312 of 364 (85.7%) isoniazid-resistant Mycobacterium tuberculosis isolates. Seven of 52 (13.5%) isoniazid-resistant isolates with the wild-type Ser315 codon and 10 of 52 (19.2%) isoniazid-resistant isolates with a mutated katG allele had mutation -15C-->T in the promoter of the mabA-inhA operon.Entities:
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Year: 2003 PMID: 12760887 PMCID: PMC155844 DOI: 10.1128/AAC.47.6.2009-2011.2003
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191