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Literature DB >> 12744700

Unsaturated nitriles: conjugate additions of carbon nucleophiles to a recalcitrant class of acceptors.

Fraser F Fleming¹, Qunzhao Wang.

Abstract

Entities: Chemical

Year: 2003 PMID： 12744700 DOI： 10.1021/cr020045d

Source DB: PubMed Journal: Chem Rev ISSN： 0009-2665 Impact factor: 60.622

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23 in total

Review 1. Nitrile-containing pharmaceuticals: efficacious roles of the nitrile pharmacophore.

Authors: Fraser F Fleming; Lihua Yao; P C Ravikumar; Lee Funk; Brian C Shook
Journal: J Med Chem Date: 2010-08-30 Impact factor: 7.446

2. A Copper-Mediated Conjugate Addition Approach to Analogues of Aconitine-Type Diterpenoid Alkaloids.

Authors: Nicolle A Doering; Kevin G M Kou; Krissada Norseeda; Jack C Lee; Christopher J Marth; Gary M Gallego; Richmond Sarpong
Journal: J Org Chem Date: 2018-09-28 Impact factor: 4.354

3. Direct Access to Versatile Electrophiles via Catalytic Oxidative Cyanation of Alkenes.

Authors: De-Wei Gao; Ekaterina V Vinogradova; Sri Krishna Nimmagadda; Jose M Medina; Yiyang Xiao; Radu M Suciu; Benjamin F Cravatt; Keary M Engle
Journal: J Am Chem Soc Date: 2018-06-22 Impact factor: 15.419

4. Synthesis of nitriles via palladium-catalyzed water shuffling from amides to acetonitrile.

Authors: Wandi Zhang; Christopher W Haskins; Yang Yang; Mingji Dai
Journal: Org Biomol Chem Date: 2014-12-07 Impact factor: 3.876

5. Predicting the reactivity of nitrile-carrying compounds with cysteine: a combined computational and experimental study.

Authors: Anna Berteotti; Federica Vacondio; Alessio Lodola; Michele Bassi; Claudia Silva; Marco Mor; Andrea Cavalli
Journal: ACS Med Chem Lett Date: 2014-02-24 Impact factor: 4.345

6. Picomolar inhibitors of HIV reverse transcriptase featuring bicyclic replacement of a cyanovinylphenyl group.

Authors: Won-Gil Lee; Ricardo Gallardo-Macias; Kathleen M Frey; Krasimir A Spasov; Mariela Bollini; Karen S Anderson; William L Jorgensen
Journal: J Am Chem Soc Date: 2013-10-24 Impact factor: 15.419

7. Mechanistic Insight Facilitates Discovery of a Mild and Efficient Copper-Catalyzed Dehydration of Primary Amides to Nitriles Using Hydrosilanes.

Authors: Richard Y Liu; Minwoo Bae; Stephen L Buchwald
Journal: J Am Chem Soc Date: 2018-01-29 Impact factor: 15.419