OBJECTIVES: To describe the short-term outcomes in Aboriginal children admitted to hospital with radiological alveolar lobar changes; and determine whether predischarge chest radiography can predict respiratory morbidity found at follow-up. DESIGN, PARTICIPANTS, SETTING: Prospective cohort study of Aboriginal children admitted to Alice Springs Hospital between October 2000 and April 2001 with alveolar lobar abnormalities (area of consolidation, > or = 1 cm) on chest radiographs. Participants were to have a predischarge radiograph and be followed up for 12 months. MAIN OUTCOME MEASURES: Comorbidities, follow-up rate, and new respiratory disease found at follow-up. RESULTS: Of 113 children hospitalised with radiological alveolar lobar changes, 109 were Aboriginal. Their median age was 1.8 years (range, 0.2 months-13.3 years), and 124 episodes were recorded. Comorbidities were common in these children (anaemia, 51.5%; suppurative otitis media, 37.3%). The follow-up rate one year after admission was 83.1% of episodes. New treatable chronic respiratory morbidity was found in 20 (25.6%) of the 78 children with completed follow-up. Predischarge chest radiographs were predictive of all chronic respiratory morbidity when they showed no or minimal resolution (0-20% resolution) (relative risk, 7.43; 95% CI, 2.07-26.60). CONCLUSIONS: Central Australian Aboriginal children admitted to hospital with alveolar changes on chest radiographs have a substantial burden of chronic respiratory illness, and should be clinically followed up for early detection and management of chronic respiratory morbidity. A predischarge radiograph is useful, and patients whose radiograph shows no or minimal resolution should have a follow-up x-ray film.
OBJECTIVES: To describe the short-term outcomes in Aboriginal children admitted to hospital with radiological alveolar lobar changes; and determine whether predischarge chest radiography can predict respiratory morbidity found at follow-up. DESIGN, PARTICIPANTS, SETTING: Prospective cohort study of Aboriginal children admitted to Alice Springs Hospital between October 2000 and April 2001 with alveolar lobar abnormalities (area of consolidation, > or = 1 cm) on chest radiographs. Participants were to have a predischarge radiograph and be followed up for 12 months. MAIN OUTCOME MEASURES: Comorbidities, follow-up rate, and new respiratory disease found at follow-up. RESULTS: Of 113 children hospitalised with radiological alveolar lobar changes, 109 were Aboriginal. Their median age was 1.8 years (range, 0.2 months-13.3 years), and 124 episodes were recorded. Comorbidities were common in these children (anaemia, 51.5%; suppurative otitis media, 37.3%). The follow-up rate one year after admission was 83.1% of episodes. New treatable chronic respiratory morbidity was found in 20 (25.6%) of the 78 children with completed follow-up. Predischarge chest radiographs were predictive of all chronic respiratory morbidity when they showed no or minimal resolution (0-20% resolution) (relative risk, 7.43; 95% CI, 2.07-26.60). CONCLUSIONS: Central Australian Aboriginal children admitted to hospital with alveolar changes on chest radiographs have a substantial burden of chronic respiratory illness, and should be clinically followed up for early detection and management of chronic respiratory morbidity. A predischarge radiograph is useful, and patients whose radiograph shows no or minimal resolution should have a follow-up x-ray film.
Authors: Anne B Chang; Keith Grimwood; Andrew V White; Carolyn Maclennan; Theo P Sloots; Alan Sive; Gabrielle B McCallum; Ian M Mackay; Peter S Morris Journal: Trials Date: 2011-04-14 Impact factor: 2.279
Authors: Anne B Chang; Siew Moy Fong; Tsin Wen Yeo; Robert S Ware; Gabrielle B McCallum; Anna M Nathan; Mong H Ooi; Jessie de Bruyne; Catherine A Byrnes; Bilawara Lee; Nachal Nachiappan; Noorazlina Saari; Paul Torzillo; Heidi Smith-Vaughan; Peter S Morris; John W Upham; Keith Grimwood Journal: BMJ Open Date: 2019-04-24 Impact factor: 2.692
Authors: André Schultz; Anne B Chang; Fenella Gill; Roz Walker; Melanie Barwick; Sarah Munns; Matthew N Cooper; Richard Norman; Pamela Laird Journal: BMC Pulm Med Date: 2022-03-17 Impact factor: 3.317
Authors: Anne B Chang; Maree Toombs; Mark D Chatfield; Remai Mitchell; Siew M Fong; Michael J Binks; Heidi Smith-Vaughan; Susan J Pizzutto; Karin Lust; Peter S Morris; Julie M Marchant; Stephanie T Yerkovich; Hannah O'Farrell; Paul J Torzillo; Carolyn Maclennan; David Simon; Holger W Unger; Hasthika Ellepola; Jens Odendahl; Helen S Marshall; Geeta K Swamy; Keith Grimwood Journal: Front Pediatr Date: 2022-01-17 Impact factor: 3.418