PURPOSE: To investigate whether ICSI (intracytoplasmic sperm injection) results in decreased blastocyst formation and pregnancy compared to IVF (in vitro fertilization). METHODS: We performed a retrospective analysis of blastocyst transfer (BT) offered routinely to patients under age 40 with > or = three 8-cell embryos on day 3 and compared IVF to ICSI cycles. Sequential media were used with P1 until day 3, then Blastocyst Medium until day 5/6. RESULTS: There were 131 IVF and 75 ICSI cycles. There was no difference in age, number of oocytes, zygotes, 8-cell embryos, blastocysts on days 5 and 6, or embryos transferred. Progression to blastocyst was similar (78% for IVF and 73% for ICSI) as was the viable pregnancy rate (51.4% for IVF and 55% for ICSI). No cycles failed to form blastocysts. CONCLUSIONS: The progression to blastocyst and the likelihood of conceiving a viable pregnancy were unaltered by ICSI. Thus it seems appropriate for programs to offer BT to patients undergoing ICSI using the same inclusion criteria applied to their IVF patients.
PURPOSE: To investigate whether ICSI (intracytoplasmic sperm injection) results in decreased blastocyst formation and pregnancy compared to IVF (in vitro fertilization). METHODS: We performed a retrospective analysis of blastocyst transfer (BT) offered routinely to patients under age 40 with > or = three 8-cell embryos on day 3 and compared IVF to ICSI cycles. Sequential media were used with P1 until day 3, then Blastocyst Medium until day 5/6. RESULTS: There were 131 IVF and 75 ICSI cycles. There was no difference in age, number of oocytes, zygotes, 8-cell embryos, blastocysts on days 5 and 6, or embryos transferred. Progression to blastocyst was similar (78% for IVF and 73% for ICSI) as was the viable pregnancy rate (51.4% for IVF and 55% for ICSI). No cycles failed to form blastocysts. CONCLUSIONS: The progression to blastocyst and the likelihood of conceiving a viable pregnancy were unaltered by ICSI. Thus it seems appropriate for programs to offer BT to patients undergoing ICSI using the same inclusion criteria applied to their IVFpatients.
Authors: J C Dumoulin; E Coonen; M Bras; L C van Wissen; R Ignoul-Vanvuchelen; J M Bergers-Jansen; J G Derhaag; J P Geraedts; J L Evers Journal: Hum Reprod Date: 2000-02 Impact factor: 6.918
Authors: Raja Z Karaki; Sadoon S Samarraie; Nagham A Younis; Tarek M Lahloub; Mohammed H Ibrahim Journal: Fertil Steril Date: 2002-01 Impact factor: 7.329
Authors: Daniela P A F Braga; Amanda S Setti; Rita C S Figueira; Assumpto Iaconelli; Edson Borges Journal: J Assist Reprod Genet Date: 2014-06-04 Impact factor: 3.412