Andreas Mohr1. 1. Department of Radiology, University of California San Francisco, 350 Parnassus Avenue, Suite 150, San Francisco, CA 94117-1349, USA. andreas.mohr@oarg.ucsf.edu
Abstract
OBJECTIVE: To evaluate the diagnostic accuracy of water-excitation (WE) 3D FLASH and fat-saturated (FS) proton density-weighted (PDw) TSE MR imaging for detecting, grading, and sizing articular cartilage lesions of the knee. DESIGN AND PATIENTS: A total of 26 patients underwent MR imaging prior to arthroscopy with the following sequences: (1) WE 3D FLASH: 28/11 ms, scan time: 4 min 58 s, flip angle: 40 degrees; (2) FS PDw TSE: 3433/15 ms, scan time: 6 min 15 s, flip angle: 180 degrees. Grade and size of the detected lesions were quantified and compared with the results of arthroscopy for each compartment. RESULTS: The sensitivity, specificity, positive and negative predictive values, and accuracy for detecting cartilage lesions were 46%, 92%, 81%, 71% and 74% for WE 3D FLASH and 91%, 98%, 96%, 94% and 95% for FS PDw TSE MR imaging. WE 3D FLASH correlated significantly with arthroscopy for grading on the patella ( P<0.0001) and the femoral trochlea ( P=0.02) and for sizing on the femoral trochlea ( P=0.03). FS PDw correlated significantly ( P<0.0001) with arthroscopy for grading and sizing on all compartments. CONCLUSION: FS PDw TSE is an accurate method for detecting, grading and sizing articular cartilage lesions of the knee and yielded superior results relative to WE 3D FLASH MR imaging.
OBJECTIVE: To evaluate the diagnostic accuracy of water-excitation (WE) 3D FLASH and fat-saturated (FS) proton density-weighted (PDw) TSE MR imaging for detecting, grading, and sizing articular cartilage lesions of the knee. DESIGN AND PATIENTS: A total of 26 patients underwent MR imaging prior to arthroscopy with the following sequences: (1) WE 3D FLASH: 28/11 ms, scan time: 4 min 58 s, flip angle: 40 degrees; (2) FS PDw TSE: 3433/15 ms, scan time: 6 min 15 s, flip angle: 180 degrees. Grade and size of the detected lesions were quantified and compared with the results of arthroscopy for each compartment. RESULTS: The sensitivity, specificity, positive and negative predictive values, and accuracy for detecting cartilage lesions were 46%, 92%, 81%, 71% and 74% for WE 3D FLASH and 91%, 98%, 96%, 94% and 95% for FS PDw TSE MR imaging. WE 3D FLASH correlated significantly with arthroscopy for grading on the patella ( P<0.0001) and the femoral trochlea ( P=0.02) and for sizing on the femoral trochlea ( P=0.03). FS PDw correlated significantly ( P<0.0001) with arthroscopy for grading and sizing on all compartments. CONCLUSION: FS PDw TSE is an accurate method for detecting, grading and sizing articular cartilage lesions of the knee and yielded superior results relative to WE 3D FLASH MR imaging.
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