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Literature DB >> 12714050

Di-iron-tyrosyl radical ribonucleotide reductases.

Abstract

New insights have been gained into the formation of the di-iron tyrosyl radical cofactor, which is essential for nucleotide reduction in the class I ribonucleotide reductases. Recent advances include Insight into the function of the tyrosyl radical in initiation of nucleotide reduction.

Entities: Chemical

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Year: 2003 PMID： 12714050 DOI： 10.1016/s1367-5931(03)00025-5

Source DB: PubMed Journal: Curr Opin Chem Biol ISSN： 1367-5931 Impact factor: 8.822

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Cited

59 in total

1. A comparison of two-electron chemistry performed by the manganese and iron heterodimer and homodimers.

Authors: Katarina Roos; Per E M Siegbahn
Journal: J Biol Inorg Chem Date: 2011-11-15 Impact factor: 3.358

2. O(2)-evolving chlorite dismutase as a tool for studying O(2)-utilizing enzymes.

Authors: Laura M K Dassama; Timothy H Yosca; Denise A Conner; Michael H Lee; Béatrice Blanc; Bennett R Streit; Michael T Green; Jennifer L DuBois; Carsten Krebs; J Martin Bollinger
Journal: Biochemistry Date: 2012-02-13 Impact factor: 3.162

3. The active form of Chlamydia trachomatis ribonucleotide reductase R2 protein contains a heterodinuclear Mn(IV)/Fe(III) cluster with S = 1 ground state.

Authors: Wei Jiang; J Martin Bollinger; Carsten Krebs
Journal: J Am Chem Soc Date: 2007-05-27 Impact factor: 15.419

Di-iron-tyrosyl radical ribonucleotide reductases.

1. A comparison of two-electron chemistry performed by the manganese and iron heterodimer and homodimers.

2. O(2)-evolving chlorite dismutase as a tool for studying O(2)-utilizing enzymes.

3. The active form of Chlamydia trachomatis ribonucleotide reductase R2 protein contains a heterodinuclear Mn(IV)/Fe(III) cluster with S = 1 ground state.

Review 4. myo-Inositol oxygenase: a radical new pathway for O(2) and C-H activation at a nonheme diiron cluster.

Review 5. Assembly of nonheme Mn/Fe active sites in heterodinuclear metalloproteins.

6. Key Structural Motifs Balance Metal Binding and Oxidative Reactivity in a Heterobimetallic Mn/Fe Protein.

7. A 2.8 Å Fe-Fe separation in the Fe2(III/IV) intermediate, X, from Escherichia coli ribonucleotide reductase.

8. Hydroxyurea induces hydroxyl radical-mediated cell death in Escherichia coli.

9. The tRNA thiolation pathway modulates the intracellular redox state in Escherichia coli.

10. Dif1 is a DNA-damage-regulated facilitator of nuclear import for ribonucleotide reductase.