Literature DB >> 12708575

Outcome in high-functioning adults with autism with and without early language delays: implications for the differentiation between autism and Asperger syndrome.

Patricia Howlin1.   

Abstract

The question of whether Asperger syndrome and high-functioning autism should be considered as the same or different conditions has been a source of debate and controversy over recent years. In the present study, 34 adults with autism who had shown early delays in language were compared with 42 individuals who were reported to have had no such delays, either in their use of words or phrases. All participants were at least 18 years of age, had a nonverbal IQ of 70 or above and met ADI-R criteria for age of onset, communication and social impairments, and stereotyped behaviors. Those in the language delay group were diagnosed as having high-functioning autism. The remainder were designated as having Asperger syndrome. The groups were matched for age, nonverbal IQ and gender. No significant differences were found between the groups either in their total ADI-R algorithm scores, or in their algorithm scores on individual domains. Social outcome ratings and ADI-R scores based on current functioning also failed to differentiate between the groups. Scores on tests of language comprehension and expression were also similar, but in both groups language abilities were well below chronological age level. The implications of these results with respect to the differences between Asperger syndrome and high-functioning autism are discussed. The poor performance on language tests also challenges the assumption that early language development in Asperger syndrome is essentially normal.

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Mesh:

Year:  2003        PMID: 12708575     DOI: 10.1023/a:1022270118899

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN: 0162-3257


  26 in total

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2.  A deficit in shifting attention present in high-functioning autism but not Asperger's disorder.

Authors:  N J Rinehart; J L Bradshaw; S A Moss; A V Brereton; B J Tonge
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3.  Comparison of clinical symptoms in autism and Asperger's disorder.

Authors:  R Eisenmajer; M Prior; S Leekam; L Wing; J Gould; M Welham; B Ong
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1996-11       Impact factor: 8.829

4.  The diagnosis of autism and Asperger syndrome: findings from a survey of 770 families.

Authors:  P Howlin; A Asgharian
Journal:  Dev Med Child Neurol       Date:  1999-12       Impact factor: 5.449

5.  A comparative study of Asperger syndrome with high-functioning atypical autism.

Authors:  H Kurita
Journal:  Psychiatry Clin Neurosci       Date:  1997-04       Impact factor: 5.188

6.  Asperger's syndrome and autism: differences in behavior, cognition, and adaptive functioning.

Authors:  P Szatmari; L Archer; S Fisman; D L Streiner; F Wilson
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1995-12       Impact factor: 8.829

7.  The external validity of Asperger disorder: lack of evidence from the domain of neuropsychology.

Authors:  J N Miller; S Ozonoff
Journal:  J Abnorm Psychol       Date:  2000-05

8.  Non-significance of early speech delay in children with autism and normal intelligence and implications for DSM-IV Asperger's disorder.

Authors:  S D Mayes; S L Calhoun
Journal:  Autism       Date:  2001-03

9.  Development and current functioning in adolescents with Asperger syndrome: a comparative study.

Authors:  A Gilchrist; J Green; A Cox; D Burton; M Rutter; A Le Couteur
Journal:  J Child Psychol Psychiatry       Date:  2001-02       Impact factor: 8.982

10.  Is clumsiness a marker for Asperger syndrome?

Authors:  M Ghaziuddin; E Butler; L Tsai; N Ghaziuddin
Journal:  J Intellect Disabil Res       Date:  1994-10
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  125 in total

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2.  Brief report: a comparison of statistical learning in school-aged children with high functioning autism and typically developing peers.

Authors:  Jessica Mayo; Inge-Marie Eigsti
Journal:  J Autism Dev Disord       Date:  2012-11

Review 3.  DSM-5 ASD moves forward into the past.

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4.  Sex-Related Cognitive Profile in Autism Spectrum Disorders Diagnosed Late in Life: Implications for the Female Autistic Phenotype.

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Journal:  J Autism Dev Disord       Date:  2016-01

Review 5.  Predictors for work participation in individuals with an Autism spectrum disorder: a systematic review.

Authors:  Anja Holwerda; Jac J L van der Klink; Johan W Groothoff; Sandra Brouwer
Journal:  J Occup Rehabil       Date:  2012-09

6.  Probabilistic reinforcement learning in adults with autism spectrum disorders.

Authors:  Marjorie Solomon; Anne C Smith; Michael J Frank; Stanford Ly; Cameron S Carter
Journal:  Autism Res       Date:  2011-03-18       Impact factor: 5.216

Review 7.  Humor in autism and Asperger syndrome.

Authors:  Viktoria Lyons; Michael Fitzgerald
Journal:  J Autism Dev Disord       Date:  2004-10

8.  BRAIN MYELINATION IN PREVALENT NEUROPSYCHIATRIC DEVELOPMENTAL DISORDERS: PRIMARY AND COMORBID ADDICTION.

Authors:  George Bartzokis
Journal:  Adolesc Psychiatry       Date:  2005

9.  Categorical and dimensional structure of autism spectrum disorders: the nosologic validity of Asperger Syndrome.

Authors:  Inge Kamp-Becker; Judith Smidt; Mardjan Ghahreman; Monika Heinzel-Gutenbrunner; Katja Becker; Helmut Remschmidt
Journal:  J Autism Dev Disord       Date:  2010-08

10.  The amygdala is enlarged in children but not adolescents with autism; the hippocampus is enlarged at all ages.

Authors:  Cynthia Mills Schumann; Julia Hamstra; Beth L Goodlin-Jones; Linda J Lotspeich; Hower Kwon; Michael H Buonocore; Cathy R Lammers; Allan L Reiss; David G Amaral
Journal:  J Neurosci       Date:  2004-07-14       Impact factor: 6.167

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