Literature DB >> 26319250

Sex-Related Cognitive Profile in Autism Spectrum Disorders Diagnosed Late in Life: Implications for the Female Autistic Phenotype.

Fritz-Georg Lehnhardt1, Christine Michaela Falter2, Astrid Gawronski2, Kathleen Pfeiffer2, Ralf Tepest2, Jeremy Franklin3, Kai Vogeley2,4.   

Abstract

Females with high-functioning ASD are known to camouflage their autistic symptoms better than their male counterparts, making them prone to being under-ascertained and delayed in diagnostic assessment. Thus far the underlying cognitive processes that enable such successful socio-communicative adaptation are not well understood. The current results show sex-related differences in the cognitive profile of ASD individuals, which were diagnosed late in life exclusively. Higher verbal abilities were found in males (n = 69) as opposed to higher processing speed and better executive functions in females with ASD (n = 38). Since both sexes remained unidentified during childhood and adolescence, these results are suggestive for sex-distinctive cognitive strategies as an alternative to typically-developed reciprocal social behavior and social mimicry in high functioning ASD.

Entities:  

Keywords:  Adulthood; Autism spectrum disorder; Cognitive profile; Female autistic phenotype; Processing speed

Mesh:

Year:  2016        PMID: 26319250     DOI: 10.1007/s10803-015-2558-7

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN: 0162-3257


  103 in total

1.  The autism diagnostic observation schedule-generic: a standard measure of social and communication deficits associated with the spectrum of autism.

Authors:  C Lord; S Risi; L Lambrecht; E H Cook; B L Leventhal; P C DiLavore; A Pickles; M Rutter
Journal:  J Autism Dev Disord       Date:  2000-06

2.  Cognitive flexibility impairments in children with autism spectrum disorders: links to age, gender and child outcomes.

Authors:  Amir Hossein Memari; Vahid Ziaee; Monir Shayestehfar; Parisa Ghanouni; Mohammad Ali Mansournia; Pouria Moshayedi
Journal:  Res Dev Disabil       Date:  2013-07-22

3.  [Psychosocial functioning of adults with late diagnosed autism spectrum disorders--a retrospective study].

Authors:  F-G Lehnhardt; A Gawronski; K Volpert; L Schilbach; R Tepest; K Vogeley
Journal:  Fortschr Neurol Psychiatr       Date:  2011-11-15       Impact factor: 0.752

4.  Non-significance of early speech delay in children with autism and normal intelligence and implications for DSM-IV Asperger's disorder.

Authors:  S D Mayes; S L Calhoun
Journal:  Autism       Date:  2001-03

5.  Comorbid psychiatric disorders in children with autism: interview development and rates of disorders.

Authors:  Ovsanna T Leyfer; Susan E Folstein; Susan Bacalman; Naomi O Davis; Elena Dinh; Jubel Morgan; Helen Tager-Flusberg; Janet E Lainhart
Journal:  J Autism Dev Disord       Date:  2006-10

6.  How different are girls and boys above and below the diagnostic threshold for autism spectrum disorders?

Authors:  Katharina Dworzynski; Angelica Ronald; Patrick Bolton; Francesca Happé
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2012-06-26       Impact factor: 8.829

7.  Autism spectrum disorders: sex differences in autistic behaviour domains and coexisting psychopathology.

Authors:  Martin Holtmann; Sven Bölte; Fritz Poustka
Journal:  Dev Med Child Neurol       Date:  2007-05       Impact factor: 5.449

Review 8.  Sex differences in autism spectrum disorders.

Authors:  Donna M Werling; Daniel H Geschwind
Journal:  Curr Opin Neurol       Date:  2013-04       Impact factor: 5.710

9.  The empathy quotient: an investigation of adults with Asperger syndrome or high functioning autism, and normal sex differences.

Authors:  Simon Baron-Cohen; Sally Wheelwright
Journal:  J Autism Dev Disord       Date:  2004-04

10.  Cognition in males and females with autism: similarities and differences.

Authors:  Meng-Chuan Lai; Michael V Lombardo; Amber N V Ruigrok; Bhismadev Chakrabarti; Sally J Wheelwright; Bonnie Auyeung; Carrie Allison; Simon Baron-Cohen
Journal:  PLoS One       Date:  2012-10-17       Impact factor: 3.240

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  33 in total

Review 1.  Women and Autism Spectrum Disorder: Diagnosis and Implications for Treatment of Adolescents and Adults.

Authors:  Renée M Green; Alyssa M Travers; Yamini Howe; Christopher J McDougle
Journal:  Curr Psychiatry Rep       Date:  2019-03-09       Impact factor: 5.285

2.  Gender Difference in the Association Between Executive Function and Autistic Traits in Typically Developing Children.

Authors:  Meixia Dai; Lizi Lin; Jingjing Liang; Zengjian Wang; Jin Jing
Journal:  J Autism Dev Disord       Date:  2019-03

Review 3.  Sex Differences in Autism Spectrum Disorder: a Review.

Authors:  Sarah L Ferri; Ted Abel; Edward S Brodkin
Journal:  Curr Psychiatry Rep       Date:  2018-03-05       Impact factor: 5.285

4.  Sex as a Moderator Between Parent Ratings of Executive Dysfunction and Social Difficulties in Children and Adolescents with Autism Spectrum Disorder.

Authors:  Tonje Torske; Terje Nærland; Daniel S Quintana; Ruth Elizabeth Hypher; Anett Kaale; Anne Lise Høyland; Sigrun Hope; Jarle Johannessen; Merete G Øie; Ole A Andreassen
Journal:  J Autism Dev Disord       Date:  2022-07-15

5.  Sex/Gender Differences in CARS2 and GARS-3 Item Scores: Evidence of Phenotypic Differences Between Males and Females with ASD.

Authors:  Joanna M Tsirgiotis; Robyn L Young; Nathan Weber
Journal:  J Autism Dev Disord       Date:  2021-09-17

6.  Social Camouflaging in Females with Autism Spectrum Disorder: A Systematic Review.

Authors:  María Tubío-Fungueiriño; Sara Cruz; Adriana Sampaio; Angel Carracedo; Montse Fernández-Prieto
Journal:  J Autism Dev Disord       Date:  2021-07

7.  Sex-Based Analysis of De Novo Variants in Neurodevelopmental Disorders.

Authors:  Tychele N Turner; Amy B Wilfert; Trygve E Bakken; Raphael A Bernier; Micah R Pepper; Zhancheng Zhang; Rebecca I Torene; Kyle Retterer; Evan E Eichler
Journal:  Am J Hum Genet       Date:  2019-11-27       Impact factor: 11.025

8.  Sex-specific autistic endophenotypes induced by prenatal exposure to valproic acid involve anandamide signalling.

Authors:  Francesca Melancia; Sara Schiavi; Michela Servadio; Veronica Cartocci; Patrizia Campolongo; Maura Palmery; Valentina Pallottini; Viviana Trezza
Journal:  Br J Pharmacol       Date:  2018-08-09       Impact factor: 8.739

9.  Valproic acid treated female Long-Evans rats are impaired on attentional set-shifting.

Authors:  Zach E McKinnell; Tessa Maze; Alejandro Ramos; Brandon Challans; Bethany Plakke
Journal:  Behav Brain Res       Date:  2020-10-11       Impact factor: 3.332

10.  Camouflaging Intent, First Impressions, and Age of ASC Diagnosis in Autistic Men and Women.

Authors:  Hannah L Belcher; Sharon Morein-Zamir; Will Mandy; Ruth M Ford
Journal:  J Autism Dev Disord       Date:  2021-08-03
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