Literature DB >> 12697644

Mechanisms of resistance to quinolones: target alterations, decreased accumulation and DNA gyrase protection.

Joaquim Ruiz1.   

Abstract

Quinolones are broad-spectrum antibacterial agents, commonly used in both clinical and veterinary medicine. Their extensive use has resulted in bacteria rapidly developing resistance to these agents. Two mechanisms of quinolone resistance have been established to date: alterations in the targets of quinolones, and decreased accumulation due to impermeability of the membrane and/or an overexpression of efflux pump systems. Recently, mobile elements have also been described, carrying the qnr gene, which confers resistance to quinolones.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12697644     DOI： 10.1093/jac/dkg222

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  200 in total

1.  Antimicrobial drug resistance trends of bacteremia isolates in a rural hospital in southern Mozambique.

Authors:  Inácio Mandomando; Betuel Sigaúque; Luis Morais; Mateu Espasa; Xavier Vallès; Jahit Sacarlal; Eusébio Macete; Pedro Aide; Llorenç Quintò; Tacilta Nhampossa; Sónia Machevo; Quique Bassat; Clara Menéndez; Joaquim Ruiz; Anna Roca; Pedro L Alonso
Journal:  Am J Trop Med Hyg       Date:  2010-07       Impact factor: 2.345

2.  Molecular typing and resistance analysis of travel-associated Salmonella enterica serotype Typhi.

Authors:  A Tatavarthy; R Sanderson; K Peak; G Scilabro; P Davenhill; A Cannons; P Amuso
Journal:  J Clin Microbiol       Date:  2012-05-30       Impact factor: 5.948

Review 3.  SOS response and its regulation on the fluoroquinolone resistance.

Authors:  Ting-Ting Qin; Hai-Quan Kang; Ping Ma; Peng-Peng Li; Lin-Yan Huang; Bing Gu
Journal:  Ann Transl Med       Date:  2015-12

4.  Mechanisms of reduced susceptibility to ciprofloxacin in Escherichia coli isolates from Canadian hospitals.

Authors:  Patricia J Baudry-Simner; Amanpreet Singh; James A Karlowsky; Daryl J Hoban; George G Zhanel
Journal:  Can J Infect Dis Med Microbiol       Date:  2012       Impact factor: 2.471

5.  Prevalence and molecular analysis of macrolide and fluoroquinolone resistance among isolates of Streptococcus pneumoniae collected during the 2000-2001 PROTEKT US Study.

Authors:  Steven D Brown; David J Farrell; Ian Morrissey
Journal:  J Clin Microbiol       Date:  2004-11       Impact factor: 5.948

6.  Further identification of plasmid-mediated quinolone resistance determinant in Enterobacteriaceae in Turkey.

Authors:  Hasan Nazic; Laurent Poirel; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2005-05       Impact factor: 5.191

7.  parC mutations in fluoroquinolone-resistant Borrelia burgdorferi.

Authors:  Kendal M Galbraith; Amanda C Ng; Betsy J Eggers; Craig R Kuchel; Christian H Eggers; D Scott Samuels
Journal:  Antimicrob Agents Chemother       Date:  2005-10       Impact factor: 5.191

8.  Association of plasmid-mediated quinolone resistance with extended-spectrum beta-lactamase VEB-1.

Authors:  Laurent Poirel; Marc Van De Loo; Hedi Mammeri; Patrice Nordmann
Journal:  Antimicrob Agents Chemother       Date:  2005-07       Impact factor: 5.191

9.  Novel approach to mapping of resistance mutations in whole genomes by using restriction enzyme modulation of transformation efficiency.

Authors:  Claude G Lerner; Stephan J Kakavas; Christian Wagner; Richard T Chang; Philip J Merta; Xiaoan Ruan; Randy E Metzger; Bruce A Beutel
Journal:  Antimicrob Agents Chemother       Date:  2005-07       Impact factor: 5.191

10.  Prevalence of Quinolone Resistance in Enterobacteriaceae from Sierra Leone and the Detection of qnrB Pseudogenes and Modified LexA Binding Sites.

Authors:  Tomasz A Leski; Michael G Stockelman; Umaru Bangura; Daniel Chae; Rashid Ansumana; David A Stenger; Gary J Vora; Chris R Taitt
Journal:  Antimicrob Agents Chemother       Date:  2016-10-21       Impact factor: 5.191
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.