Literature DB >> 1269626

[Structure-activity relationship of human calcitonin. III. Biological activity of synthetic analogues with shortened or terminally modified peptide chains (author's transl)].

W Rittel, R Maier, M Brugger, B Kamber, B Riniker, P Sieber.   

Abstract

Assays of 8 synthetic analogues of human calcitonin in rats showed that their hypocalcaemic activity was drastically reduced by deletion of the C-terminal amide group, chain-shortening or opening of the disulphide ring, but unaffected or enhanced by modification of the N-terminal amino group.

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Year:  1976        PMID： 1269626     DOI： 10.1007/BF01937791

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  5 in total

1.  Immunochemical studies on human calcitonin M leading to information on the shape of the molecule.

Authors:  P G Byfield; M B Clark; K Turner; G V Foster; I MacIntyre
Journal:  Biochem J       Date:  1972-03       Impact factor: 3.857

2.  [Human calcitonin. VI. Synthesis of calcitonin M].

Authors:  P Sieber; B Riniker; M Brugger; B Kamber; W Rittel
Journal:  Helv Chim Acta       Date:  1970       Impact factor: 2.164

3.  [Human calcitonin. Structure of calcitonin M and D].

Authors:  R Neher; B Riniker; W Rittel; H Zuber
Journal:  Helv Chim Acta       Date:  1968       Impact factor: 2.164

4.  [Thyrocalcitonin. IV. The total synthesis of alpha-thyrocalcitonin].

Authors:  B Riniker; M Brugger; B Kamber; P Sieber; W Rittel
Journal:  Helv Chim Acta       Date:  1969       Impact factor: 2.164

5.  A biological assay for calcitonin.

Authors:  M A Kumar; E Slack; A Edwards; H A Soliman; A Baghdiantz; G V Foster; I MacIntyre
Journal:  J Endocrinol       Date:  1965-11       Impact factor: 4.286
  5 in total
  9 in total

Review 1.  Peptides from the calcitonin genes: molecular genetics, structure and function.

Authors:  L H Breimer; I MacIntyre; M Zaidi
Journal:  Biochem J       Date:  1988-10-15       Impact factor: 3.857

2.  Calcitonin and calcium ionophores: cyclic AMP responses in cells of a human lymphoid line.

Authors:  J Moran; W Hunziker; J A Fischer
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

3.  Conformational transitions and fibrillation mechanism of human calcitonin as studied by high-resolution solid-state 13C NMR.

Authors:  M Kamihira; A Naito; S Tuzi; A Y Nosaka; H Saitô
Journal:  Protein Sci       Date:  2000-05       Impact factor: 6.725

4.  Human calcitonin gene-related peptide possesses weak inhibitory potency of bone resorption in vitro.

Authors:  I Yamamoto; N Kitamura; J Aoki; C Shigeno; M Hino; K Asonuma; K Torizuka; N Fujii; A Otaka; H Yajima
Journal:  Calcif Tissue Int       Date:  1986-06       Impact factor: 4.333

5.  Synthesis of eel-calcitonin and (asu1,7)-eel-calcitonin: contribution of the disulfide bond to the hormonal activity.

Authors:  T Morikawa; E Munekata; S Sakakibara; T Noda; M Otani
Journal:  Experientia       Date:  1976-09-15

6.  Characterization of the immunochemical forms of calcitonin released by a medullary thyroid carcinoma in tissue culture.

Authors:  D Goltzman; A S Tischler
Journal:  J Clin Invest       Date:  1978-02       Impact factor: 14.808

Review 7.  Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development.

Authors:  Rebekah L Bower; Debbie L Hay
Journal:  Br J Pharmacol       Date:  2016-05-18       Impact factor: 8.739

8.  A comparison of the effects of amide and acid groups at the C-terminus on the collision-induced dissociation of deprotonated peptides.

Authors:  Samantha S Bokatzian-Johnson; Michele L Stover; David A Dixon; Carolyn J Cassady
Journal:  J Am Soc Mass Spectrom       Date:  2012-07-26       Impact factor: 3.109

Review 9.  Pharmacology and therapeutic use of calcitonin.

Authors:  J C Stevenson; I M Evans
Journal:  Drugs       Date:  1981-04       Impact factor: 9.546
  9 in total

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