Literature DB >> 12689326

Bubble dynamics in double-stranded DNA.

Grégoire Altan-Bonnet1, Albert Libchaber, Oleg Krichevsky.   

Abstract

We report the first measurement of the dynamics of bubble formation in double-stranded DNA. Fluctuations of fluorescence of a synthetic DNA construct, internally tagged with a fluorophore and a quencher, are monitored by fluorescence correlation spectroscopy. The relaxation dynamics follow a multistate relaxation kinetics, with a characteristic time scale of 50 microseconds. A simple model of bubble dynamics based on constant zipping-unzipping rates is proposed to account for our experimental data. The role of different secondary structures stabilizing the open bubble is tested.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12689326     DOI： 10.1103/PhysRevLett.90.138101

Source DB:  PubMed          Journal:  Phys Rev Lett        ISSN： 0031-9007            Impact factor:   9.161


  53 in total

1.  Dynamics of the DNA duplex formation studied by single molecule force measurements.

Authors:  U Bockelmann; P Thomen; F Heslot
Journal:  Biophys J       Date:  2004-08-31       Impact factor: 4.033

2.  DNA as a programmable viscoelastic nanoelement.

Authors:  Richard A Neher; Ulrich Gerland
Journal:  Biophys J       Date:  2005-09-30       Impact factor: 4.033

3.  Direct observation of DNA bending/unbending kinetics in complex with DNA-bending protein IHF.

Authors:  Serguei V Kuznetsov; Sawako Sugimura; Paula Vivas; Donald M Crothers; Anjum Ansari
Journal:  Proc Natl Acad Sci U S A       Date:  2006-11-21       Impact factor: 11.205

4.  Force-induced DNA slippage.

Authors:  Ferdinand Kühner; Julia Morfill; Richard A Neher; Kerstin Blank; Hermann E Gaub
Journal:  Biophys J       Date:  2007-01-11       Impact factor: 4.033

5.  Breathing dynamics in heteropolymer DNA.

Authors:  Tobias Ambjörnsson; Suman K Banik; Oleg Krichevsky; Ralf Metzler
Journal:  Biophys J       Date:  2007-01-19       Impact factor: 4.033

6.  Bubbles and denaturation in DNA.

Authors:  T S van Erp; S Cuesta-López; M Peyrard
Journal:  Eur Phys J E Soft Matter       Date:  2006-09-07       Impact factor: 1.890

7.  Disorder in DNA-linked gold nanoparticle assemblies.

Authors:  Nolan C Harris; Ching-Hwa Kiang
Journal:  Phys Rev Lett       Date:  2005-07-21       Impact factor: 9.161

8.  Modelling and inference reveal nonlinear length-dependent suppression of somatic instability for small disease associated alleles in myotonic dystrophy type 1 and Huntington disease.

Authors:  Catherine F Higham; Darren G Monckton
Journal:  J R Soc Interface       Date:  2013-09-18       Impact factor: 4.118

9.  Mean-field interactions between nucleic-acid-base dipoles can drive the formation of a double helix.

Authors:  Yi He; Maciej Maciejczyk; Stanisław Ołdziej; Harold A Scheraga; Adam Liwo
Journal:  Phys Rev Lett       Date:  2013-02-28       Impact factor: 9.161

10.  Fluorescence correlation spectroscopy in living cells: a practical approach.

Authors:  Nihal Altan-Bonnet; Grégoire Altan-Bonnet
Journal:  Curr Protoc Cell Biol       Date:  2009-12
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.