| Literature DB >> 12676722 |
Keith R Shockley1, Donald E Ward, Swapnil R Chhabra, Shannon B Conners, Clemente I Montero, Robert M Kelly.
Abstract
Collective transcriptional analysis of heat shock response in the hyperthermophilic archaeon Pyrococcus furiosus was examined by using a targeted cDNA microarray in conjunction with Northern analyses. Differential gene expression suggests that P. furiosus relies on a cooperative strategy of rescue (thermosome [Hsp60], small heat shock protein [Hsp20], and two VAT-related chaperones), proteolysis (proteasome), and stabilization (compatible solute formation) to cope with polypeptide processing during thermal stress.Entities:
Mesh:
Substances:
Year: 2003 PMID: 12676722 PMCID: PMC154833 DOI: 10.1128/AEM.69.4.2365-2371.2003
Source DB: PubMed Journal: Appl Environ Microbiol ISSN: 0099-2240 Impact factor: 4.792