Literature DB >> 12668006

Leporin B: a novel hexokinase II gene inducing agent from an unidentified fungus.

Chaowei Zhang1, Liang Jin, Belinda Mondie, Scott S Mitchell, Arlindo L Castelhano, Weizhong Cai, Nils Bergenhem.   

Abstract

Leporin B (1), a novel demethylated analogue of leporin A (2), was isolated from a taxonomically unidentified fungal strain as part of an effort to discover compounds with the ability to increase expression levels of the enzyme hexokinase II. The structure was determined by spectral methods, including 1D and 2D NMR, and HRMS. The relative stereochemistry was assigned by NOESY experiments and coupling constants.

Mesh:

Substances:

Year:  2003        PMID: 12668006     DOI: 10.1016/s0960-894x(03)00153-7

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  6 in total

1.  Biomimetic conversion of (-)-fusoxypyridone and (-)-oxysporidinone to (-)-sambutoxin: further evidence for the structure of the tricyclic pyridone alkaloid, (-)-fusoxypyridone.

Authors:  E M Kithsiri Wijeratne; A A Leslie Gunatilaka
Journal:  Bioorg Med Chem Lett       Date:  2011-03-16       Impact factor: 2.823

2.  Spiroscytalin, a new tetramic acid and other metabolites of mixed biogenesis from Scytalidium cuboideum.

Authors:  Arlene A Sy-Cordero; Mario Figueroa; Huzefa A Raja; Maria Elena Meza Aviña; Mitchell P Croatt; Audrey F Adcock; David J Kroll; Mansukh C Wani; Cedric J Pearce; Nicholas H Oberlies
Journal:  Tetrahedron       Date:  2015-11-25       Impact factor: 2.457

3.  Indole diterpenoids and isocoumarin from the fungus, Aspergillus flavus, isolated from the prawn, Penaeus vannamei.

Authors:  Kunlai Sun; Ye Li; Lei Guo; Yi Wang; Peipei Liu; Weiming Zhu
Journal:  Mar Drugs       Date:  2014-06-30       Impact factor: 5.118

4.  Carbon Dioxide Mediates the Response to Temperature and Water Activity Levels in Aspergillus flavus during Infection of Maize Kernels.

Authors:  Matthew K Gilbert; Angel Medina; Brian M Mack; Matthew D Lebar; Alicia Rodríguez; Deepak Bhatnagar; Naresh Magan; Gregory Obrian; Gary Payne
Journal:  Toxins (Basel)       Date:  2017-12-22       Impact factor: 4.546

5.  2-Pyridone natural products as inhibitors of SARS-CoV-2 main protease.

Authors:  Katrina L Forrestall; Darcy E Burley; Meghan K Cash; Ian R Pottie; Sultan Darvesh
Journal:  Chem Biol Interact       Date:  2020-12-02       Impact factor: 5.192

6.  Secondary Metabolites with α-Glucosidase Inhibitory Activity from Mangrove Endophytic Fungus Talaromyces sp. CY-3.

Authors:  Wencong Yang; Qi Tan; Yihao Yin; Yan Chen; Yi Zhang; Jianying Wu; Leyao Gao; Bo Wang; Zhigang She
Journal:  Mar Drugs       Date:  2021-08-28       Impact factor: 5.118

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.