| Literature DB >> 12668006 |
Chaowei Zhang1, Liang Jin, Belinda Mondie, Scott S Mitchell, Arlindo L Castelhano, Weizhong Cai, Nils Bergenhem.
Abstract
Leporin B (1), a novel demethylated analogue of leporin A (2), was isolated from a taxonomically unidentified fungal strain as part of an effort to discover compounds with the ability to increase expression levels of the enzyme hexokinase II. The structure was determined by spectral methods, including 1D and 2D NMR, and HRMS. The relative stereochemistry was assigned by NOESY experiments and coupling constants.Mesh:
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Year: 2003 PMID: 12668006 DOI: 10.1016/s0960-894x(03)00153-7
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN: 0960-894X Impact factor: 2.823