| Literature DB >> 12657135 |
Dag R Sorensen1, Tracy-Ann Read.
Abstract
Endostatin, the 20 kDa C-terminal fragment of collagen XVIII, has been shown to be an effective inhibitor of tumour angiogenesis and growth in different experimental systems and is currently in Phase II/III clinical trials. One challenging aspect of anti-angiogenic treatment is the mode of delivery of the active compound. In this paper we review some of the basic knowledge of endostatin and look specifically into the different possible ways in which endostatin may be administered.Entities:
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Year: 2002 PMID： 12657135 PMCID： PMC2517693 DOI： 10.1046/j.1365-2613.2002.00240.x
Source DB: PubMed Journal: Int J Exp Pathol ISSN： 0959-9673 Impact factor: 1.925