Literature DB >> 12654679

In vitro metronidazole and tinidazole activities against metronidazole-resistant strains of Trichomonas vaginalis.

Andrea L Crowell1, Kolby A Sanders-Lewis, W Evan Secor.   

Abstract

The in vitro activities of tinidazole and metronidazole against Trichomonas vaginalis isolates clinically resistant to metronidazole were compared. Minimal lethal concentrations (MLCs) of tinidazole were significantly lower than MLCs of metronidazole. Increased metronidazole resistance correlated with increased tinidazole resistance. These data support a role for tinidazole in the treatment of trichomoniasis.

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Year:  2003        PMID： 12654679      PMCID： PMC152533          DOI： 10.1128/AAC.47.4.1407-1409.2003

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  21 in total

1.  Why is Trichomonas vaginalis ignored?

Authors:  F J Bowden; G P Garnett
Journal:  Sex Transm Infect       Date:  1999-12       Impact factor: 3.519

2.  Consider diagnosis and treatment of trichomoniasis in men.

Authors:  J N Krieger
Journal:  Sex Transm Dis       Date:  2000-04       Impact factor: 2.830

Review 3.  Estimates of the incidence and prevalence of sexually transmitted diseases in the United States. American Social Health Association Panel.

Authors:  W Cates
Journal:  Sex Transm Dis       Date:  1999-04       Impact factor: 2.830

4.  Trichomonal Vaginitis Resistant to Metranidazole.

Authors:  S C Robinson
Journal:  Can Med Assoc J       Date:  1962-04-07       Impact factor: 8.262

5.  Trichomonas vaginalis as a cause of urethritis in Malawian men.

Authors:  M M Hobbs; P Kazembe; A W Reed; W C Miller; E Nkata; D Zimba; C C Daly; H Chakraborty; M S Cohen; I Hoffman
Journal:  Sex Transm Dis       Date:  1999-08       Impact factor: 2.830

Review 6.  Clinical and microbiological aspects of Trichomonas vaginalis.

Authors:  D Petrin; K Delgaty; R Bhatt; G Garber
Journal:  Clin Microbiol Rev       Date:  1998-04       Impact factor: 26.132

7.  Tinidazole therapy for metronidazole-resistant vaginal trichomoniasis.

Authors:  J D Sobel; P Nyirjesy; W Brown
Journal:  Clin Infect Dis       Date:  2001-09-17       Impact factor: 9.079

8.  Strain of Trichomonas vaginalis resistant to metronidazole and other 5-nitroimidazoles.

Authors:  J G Meingassner; J Thurner
Journal:  Antimicrob Agents Chemother       Date:  1979-02       Impact factor: 5.191

9.  Mechanisms of in vitro development of resistance to metronidazole in Trichomonas vaginalis.

Authors:  Dominique Rasoloson; Stepanka Vanacova; Eva Tomkova; Jakub Razga; Ivan Hrdy; Jan Tachezy; Jaroslav Kulda
Journal:  Microbiology       Date:  2002-08       Impact factor: 2.777

10.  In vitro susceptibility of Trichomonas vaginalis to metronidazole and treatment outcome in vaginal trichomoniasis.

Authors:  M Müller; J G Lossick; T E Gorrell
Journal:  Sex Transm Dis       Date:  1988 Jan-Mar       Impact factor: 2.830
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  26 in total

1.  Activities of dicationic compounds against Trichomonas vaginalis.

Authors:  Andrea L Crowell; Chad E Stephens; Arvind Kumar; David W Boykin; W Evan Secor
Journal:  Antimicrob Agents Chemother       Date:  2004-09       Impact factor: 5.191

2.  Prevalence of Trichomonas vaginalis isolates with resistance to metronidazole and tinidazole.

Authors:  Jane R Schwebke; Frank J Barrientes
Journal:  Antimicrob Agents Chemother       Date:  2006-09-25       Impact factor: 5.191

Review 3.  Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by "amitochondriate" protozoan parasites.

Authors:  Vahab Ali; Tomoyoshi Nozaki
Journal:  Clin Microbiol Rev       Date:  2007-01       Impact factor: 26.132

4.  5-Nitroimidazole drugs effective against metronidazole-resistant Trichomonas vaginalis and Giardia duodenalis.

Authors:  Jacqueline A Upcroft; Linda A Dunn; Janelle M Wright; Kamel Benakli; Peter Upcroft; Patrice Vanelle
Journal:  Antimicrob Agents Chemother       Date:  2006-01       Impact factor: 5.191

5.  A rapid, high-throughput viability assay for Blastocystis spp. reveals metronidazole resistance and extensive subtype-dependent variations in drug susceptibilities.

Authors:  Haris Mirza; Joshua D W Teo; Jacqui Upcroft; Kevin S W Tan
Journal:  Antimicrob Agents Chemother       Date:  2010-11-22       Impact factor: 5.191

6.  Sexually transmitted diseases treatment guidelines, 2015.

Authors:  Kimberly A Workowski; Gail A Bolan
Journal:  MMWR Recomm Rep       Date:  2015-06-05

7.  Trichomonas vaginalis: treatment questions and challenges.

Authors:  W Evan Secor
Journal:  Expert Rev Anti Infect Ther       Date:  2012-02       Impact factor: 5.091

Review 8.  Natural and synthetic compound anti-Trichomonas vaginalis: an update review.

Authors:  Patrícia de Brum Vieira; Raquel Brandt Giordani; Alexandre José Macedo; Tiana Tasca
Journal:  Parasitol Res       Date:  2015-02-18       Impact factor: 2.289

Review 9.  Management of Resistant Trichomoniasis.

Authors:  Cynthia Alessio; Paul Nyirjesy
Journal:  Curr Infect Dis Rep       Date:  2019-08-06       Impact factor: 3.725

Review 10.  Getting trichy: tools and approaches to interrogating Trichomonas vaginalis in a post-genome world.

Authors:  Melissa D Conrad; Martina Bradic; Sally D Warring; Andrew W Gorman; Jane M Carlton
Journal:  Trends Parasitol       Date:  2012-12-05
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