Literature DB >> 12646356

Linus Pauling and sickle cell disease.

William A Eaton1.   

Abstract

The 1949 paper by Linus Pauling et al. [Science 110 (1949) 543-548] describing the discovery of sickle cell anemia as the first molecular disease had a major impact on biology and medicine. Inspired by the scholarly works of John Edsall on the history of hemoglobin research, I present a brief retrospective analysis of Pauling's paper. This is followed by some personal recollections of Edsall and Pauling.

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Year:  2003        PMID: 12646356     DOI: 10.1016/s0301-4622(02)00269-7

Source DB:  PubMed          Journal:  Biophys Chem        ISSN: 0301-4622            Impact factor:   2.352


  15 in total

1.  Understanding the shape of sickled red cells.

Authors:  Garrott W Christoph; James Hofrichter; William A Eaton
Journal:  Biophys J       Date:  2004-11-12       Impact factor: 4.033

2.  Anisotropy of the Coulomb interaction between folded proteins: consequences for mesoscopic aggregation of lysozyme.

Authors:  Ho Yin Chan; Vladimir Lankevich; Peter G Vekilov; Vassiliy Lubchenko
Journal:  Biophys J       Date:  2012-04-18       Impact factor: 4.033

3.  Free heme and the polymerization of sickle cell hemoglobin.

Authors:  Veselina V Uzunova; Weichun Pan; Oleg Galkin; Peter G Vekilov
Journal:  Biophys J       Date:  2010-09-22       Impact factor: 4.033

4.  Treating sickle cell anemia.

Authors:  John F Tisdale; Swee Lay Thein; William A Eaton
Journal:  Science       Date:  2020-03-13       Impact factor: 47.728

Review 5.  Metabolomic and molecular insights into sickle cell disease and innovative therapies.

Authors:  Morayo G Adebiyi; Jeanne M Manalo; Yang Xia
Journal:  Blood Adv       Date:  2019-04-23

Review 6.  Treating sickle cell disease by targeting HbS polymerization.

Authors:  William A Eaton; H Franklin Bunn
Journal:  Blood       Date:  2017-04-06       Impact factor: 22.113

7.  The Molecular Basis of Evolution and Disease: A Cold War Alliance.

Authors:  Edna Suárez-Díaz
Journal:  J Hist Biol       Date:  2019-06       Impact factor: 1.326

8.  Effect of chain chirality on the self-assembly of sickle hemoglobin.

Authors:  Xuejin Li; Bruce Caswell; George Em Karniadakis
Journal:  Biophys J       Date:  2012-09-19       Impact factor: 4.033

9.  Determination of the transition-state entropy for aggregation suggests how the growth of sickle cell hemoglobin polymers can be slowed.

Authors:  Peter G Vekilov; Oleg Galkin; B Montgomery Pettitt; Nihar Choudhury; Ronald L Nagel
Journal:  J Mol Biol       Date:  2008-01-16       Impact factor: 5.469

10.  Zebrafish globin switching occurs in two developmental stages and is controlled by the LCR.

Authors:  Jared J Ganis; Nelson Hsia; Eirini Trompouki; Jill L O de Jong; Anthony DiBiase; Janelle S Lambert; Zhiying Jia; Peter J Sabo; Molly Weaver; Richard Sandstrom; John A Stamatoyannopoulos; Yi Zhou; Leonard I Zon
Journal:  Dev Biol       Date:  2012-04-19       Impact factor: 3.582

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