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Literature DB >> 1263263

Coenzymes as fossils of an earlier metabolic state.

Abstract

A metabolic system composed of nucleic acid enzymes is proposed to have existed prior to the evolution of ribosomal protein synthesis. Vestiges of these nucleic acid enzymes persist in contemporary coenzymes. This proposal rationalizes the fact that many coenzymes are nucleotides or heterocyclic bases which could be derived from nucleotides.

Mesh：

Substances：
Coenzymes

Year: 1976 PMID： 1263263 DOI： 10.1007/BF01732468

Source DB: PubMed Journal: J Mol Evol ISSN： 0022-2844 Impact factor: 2.395

9 in total

Review 1. The evolution of dehydrogenases and kinases.

Authors: W Eventoff; M G Rossmann
Journal: CRC Crit Rev Biochem Date: 1975-08

2. AN APPROACH TO THE EVOLUTION OF METABOLISM.

Authors: R E Eakin
Journal: Proc Natl Acad Sci U S A Date: 1963-03 Impact factor: 11.205

3. Beta structures of alternating polypeptides and their possible prebiotic significance.

Authors: A Brack; L E Orgel
Journal: Nature Date: 1975-07-31 Impact factor: 49.962

4. Chemical and biological evolution of nucleotide-binding protein.

Authors: M G Rossmann; D Moras; K W Olsen
Journal: Nature Date: 1974-07-19 Impact factor: 49.962

5. A proposed model for interaction of polypeptides with RNA.

Authors: C W Carter; J Kraut
Journal: Proc Natl Acad Sci U S A Date: 1974-02 Impact factor: 11.205

6. [Catalytic role for RNA in DNA replication].

Authors: N Brewin
Journal: Nat New Biol Date: 1972-03-29

7. On earlier states of the biochemical system.

Authors: M Ycas
Journal: J Theor Biol Date: 1974-03 Impact factor: 2.691

Review 8. Self-organization of molecular systems and evolution of the genetic apparatus.

Authors: H Kuhn
Journal: Angew Chem Int Ed Engl Date: 1972-09 Impact factor: 15.336

Review 9. Selforganization of matter and the evolution of biological macromolecules.

Authors: M Eigen
Journal: Naturwissenschaften Date: 1971-10

9 in total

142 in total

1. Structural diversity of self-cleaving ribozymes.

Authors: J Tang; R R Breaker
Journal: Proc Natl Acad Sci U S A Date: 2000-05-23 Impact factor: 11.205

2. Surviving an Oxygen Atmosphere: DNA Damage and Repair.

Authors: Cynthia J Burrows
Journal: ACS Symp Ser Am Chem Soc Date: 2009-12-20

Review 3. Novel modifications in RNA.

Authors: Kelly Phelps; Alexi Morris; Peter A Beal
Journal: ACS Chem Biol Date: 2011-12-23 Impact factor: 5.100

Coenzymes as fossils of an earlier metabolic state.

Review 1. The evolution of dehydrogenases and kinases.

2. AN APPROACH TO THE EVOLUTION OF METABOLISM.

3. Beta structures of alternating polypeptides and their possible prebiotic significance.

4. Chemical and biological evolution of nucleotide-binding protein.

5. A proposed model for interaction of polypeptides with RNA.

6. [Catalytic role for RNA in DNA replication].

7. On earlier states of the biochemical system.

Review 8. Self-organization of molecular systems and evolution of the genetic apparatus.

Review 9. Selforganization of matter and the evolution of biological macromolecules.

1. Structural diversity of self-cleaving ribozymes.

2. Surviving an Oxygen Atmosphere: DNA Damage and Repair.

Review 3. Novel modifications in RNA.

4. Use of a coenzyme by the glmS ribozyme-riboswitch suggests primordial expansion of RNA chemistry by small molecules.

Review 5. The early phases of genetic code origin: conjectures on the evolution of coded catalysis.

6. Metabolite-binding RNA domains are present in the genes of eukaryotes.

7. Optimal alphabets for an RNA world.

8. Some consequences of the RNA world hypothesis.

9. Alarmones as Vestiges of a Bygone RNA World.

10. Enzymatic synthesis of polymers containing nicotinamide mononucleotide.