Literature DB >> 12628347

Transcriptional repression by Myc.

Michael Wanzel1, Steffi Herold, Martin Eilers.   

Abstract

The Myc oncoprotein is a transcription factor that can both activate and repress genes. Transcriptional activation by Myc is well understood, but, by contrast, the mechanisms through which Myc represses transcription have remained elusive. Recent evidence suggests that complex formation by Myc with a zinc-finger transcription factor, Miz-1, plays an important role in mediating repression by Myc. The findings might explain how Myc interferes with cell-cycle arrest in response to TGF-beta, APC and DNA damage.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12628347     DOI： 10.1016/s0962-8924(03)00003-5

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  67 in total

1.  Myc degradation: dancing with ubiquitin ligases.

Authors:  Bruno Amati
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-08       Impact factor: 11.205

2.  c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation.

Authors:  Anne Wilson; Mark J Murphy; Thordur Oskarsson; Konstantinos Kaloulis; Michael D Bettess; Gabriela M Oser; Anne-Catherine Pasche; Christian Knabenhans; H Robson Macdonald; Andreas Trumpp
Journal:  Genes Dev       Date:  2004-11-15       Impact factor: 11.361

3.  Myc represses transcription through recruitment of DNA methyltransferase corepressor.

Authors:  Carmen Brenner; Rachel Deplus; Céline Didelot; Axelle Loriot; Emmanuelle Viré; Charles De Smet; Arantxa Gutierrez; Davide Danovi; David Bernard; Thierry Boon; Pier Giuseppe Pelicci; Bruno Amati; Tony Kouzarides; Yvan de Launoit; Luciano Di Croce; François Fuks
Journal:  EMBO J       Date:  2004-12-16       Impact factor: 11.598

4.  Deregulation of common genes by c-Myc and its direct target, MT-MC1.

Authors:  Kenneth R Rogulski; Debra E Cohen; David L Corcoran; Panayiotis V Benos; Edward V Prochownik
Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-19       Impact factor: 11.205

5.  Host cell factor-1 and E2F4 interact via multiple determinants in each protein.

Authors:  Jozo Knez; David Piluso; Patricia Bilan; John P Capone
Journal:  Mol Cell Biochem       Date:  2006-04-22       Impact factor: 3.396

Review 6.  Balance of Yin and Yang: ubiquitylation-mediated regulation of p53 and c-Myc.

Authors:  Mu-Shui Dai; Yetao Jin; Jayme R Gallegos; Hua Lu
Journal:  Neoplasia       Date:  2006-08       Impact factor: 5.715

Review 7.  Learning the molecular mechanisms of the reprogramming factors: let's start from microRNAs.

Authors:  Chao-Shun Yang; Tariq M Rana
Journal:  Mol Biosyst       Date:  2012-10-05

8.  The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60.

Authors:  Jagruti H Patel; Yanping Du; Penny G Ard; Charles Phillips; Beth Carella; Chi-Ju Chen; Carrie Rakowski; Chandrima Chatterjee; Paul M Lieberman; William S Lane; Gerd A Blobel; Steven B McMahon
Journal:  Mol Cell Biol       Date:  2004-12       Impact factor: 4.272

9.  Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma.

Authors:  Liping Song; Tasnim Ara; Hong-Wei Wu; Chan-Wook Woo; C Patrick Reynolds; Robert C Seeger; Yves A DeClerck; Carol J Thiele; Richard Sposto; Leonid S Metelitsa
Journal:  J Clin Invest       Date:  2007-09       Impact factor: 14.808

10.  Inhibition of Myc-induced cell transformation by brain acid-soluble protein 1 (BASP1).

Authors:  Markus Hartl; Andrea Nist; M Imran Khan; Taras Valovka; Klaus Bister
Journal:  Proc Natl Acad Sci U S A       Date:  2009-03-18       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.