Literature DB >> 12616023

MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study.

Clare M C Tempany1, Elizabeth A Stewart, Nathan McDannold, Bradley J Quade, Ferenc A Jolesz, Kullervo Hynynen.   

Abstract

The feasibility and safety of magnetic resonance (MR) imaging-guided focused ultrasound surgery for uterine leiomyomas is reported. Sequential sonications were delivered to nine targets. Temperature-sensitive phase-difference MR imaging monitored the location of the focus and measured tissue temperature elevations, ensuring therapeutic dose. MR images and hysterectomy specimens were evaluated. Six leiomyomas received full therapeutic doses, and 98.5% of the sonications were visualized. MR thermometry was successful in all sonications and cases. Focal necrotic lesions were seen in all cases at MR, and five were pathologically confirmed. MR imaging-guided focused ultrasound causes thermocoagulation and necrosis in uterine leiomyomas and is feasible and safe, without serious consequences.

Entities:  

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Year:  2003        PMID： 12616023     DOI： 10.1148/radiol.2271020395

Source DB:  PubMed          Journal:  Radiology        ISSN： 0033-8419            Impact factor:   11.105


  136 in total

1.  [Focused ultrasound surgery. Basics, current status, and new trends].

Authors:  J W Jenne; G Divkovic; R Rastert; J Debus; P E Huber
Journal:  Radiologe       Date:  2003-10       Impact factor: 0.635

Review 2.  [Magnetic resonance tomography guided focussed ultrasound surgery (MRgFUS) in tumor therapy--a new noninvasive therapy option].

Authors:  S A Hengst; T Ehrenstein; H Herzog; A Beck; I Utz-Billing; M David; R Felix; J Ricke
Journal:  Radiologe       Date:  2004-04       Impact factor: 0.635

3.  Comparison between diffusion-weighted imaging, T2-weighted, and postcontrast T1-weighted imaging after MR-guided, high intensity, focused ultrasound treatment of uterine leiomyomata: preliminary results.

Authors:  Michael A Jacobs; David H Gultekin; Hyun S Kim
Journal:  Med Phys       Date:  2010-09       Impact factor: 4.071

Review 4.  High-Intensity Focused Ultrasound: Current Status for Image-Guided Therapy.

Authors:  Alexander Copelan; Jason Hartman; Monzer Chehab; Aradhana M Venkatesan
Journal:  Semin Intervent Radiol       Date:  2015-12       Impact factor: 1.513

5.  Quantitative Ultrasound for Monitoring High-Intensity Focused Ultrasound Treatment In Vivo.

Authors:  Goutam Ghoshal; Jeremy P Kemmerer; Chandra Karunakaran; Rita J Miller; Michael L Oelze
Journal:  IEEE Trans Ultrason Ferroelectr Freq Control       Date:  2016-01-14       Impact factor: 2.725

6.  Intracellular delivery of Bak BH3 peptide by microbubble-enhanced ultrasound.

Authors:  Manabu Kinoshita; Kullervo Hynynen
Journal:  Pharm Res       Date:  2005-05-17       Impact factor: 4.200

7.  Application of Zernike polynomials towards accelerated adaptive focusing of transcranial high intensity focused ultrasound.

Authors:  Elena A Kaye; Yoni Hertzberg; Michael Marx; Beat Werner; Gil Navon; Marc Levoy; Kim Butts Pauly
Journal:  Med Phys       Date:  2012-10       Impact factor: 4.071

Review 8.  Clinical and Technical Aspects of MR-Guided High Intensity Focused Ultrasound for Treatment of Symptomatic Uterine Fibroids.

Authors:  Laura E Rueff; Steven S Raman
Journal:  Semin Intervent Radiol       Date:  2013-12       Impact factor: 1.513

9.  Short-duration-focused ultrasound stimulation of Hsp70 expression in vivo.

Authors:  D E Kruse; M A Mackanos; C E O'Connell-Rodwell; C H Contag; K W Ferrara
Journal:  Phys Med Biol       Date:  2008-06-19       Impact factor: 3.609

10.  Transcranial magnetic resonance imaging- guided focused ultrasound surgery of brain tumors: initial findings in 3 patients.

Authors:  Nathan McDannold; Greg T Clement; Peter Black; Ferenc Jolesz; Kullervo Hynynen
Journal:  Neurosurgery       Date:  2010-02       Impact factor: 4.654
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