Literature DB >> 12607120

Does anastomotic leakage affect functional outcome after rectal resection for cancer?

Birgit Bittorf1, Uwe Stadelmaier, Susanne Merkel, Werner Hohenberger, Klaus E Matzel.   

Abstract

BACKGROUND: Anastomotic leakage is the most threatening early complication in sphincter-preserving rectal cancer surgery. While the oncological consequences have been well examined, only few data exist about the functional outcome. PATIENTS AND METHODS: We investigated continence function in 150 patients after curative sphincter-preserving rectal cancer surgery. Functional results were compared in 22 patients with a clinically relevant anastomotic leakage, confirmed radiologically or endoscopically, and 128 patients with uneventful recovery. Evaluation of continence function was based on the Cleveland Clinic Continence Score and was examined in all patients with anastomotic leakage and in 111 patients without complications 107+/-46 weeks postoperatively. Additionally, 14 patients with anastomotic leakage and 58 patients with uneventful recovery underwent anorectal manometry 26+/-15 weeks postoperatively.
RESULTS: The continence score in patients after anastomotic leakage did not differ significantly from that in patients without complications. Sphincter function was similar. Maximum tolerable volume and rectal compliance were slightly but not significantly worse after leakage.
CONCLUSIONS: Continence function remained undisturbed after anastomotic leakage due to rectal resection

Entities:  

Mesh:

Year:  2003        PMID: 12607120     DOI: 10.1007/s00423-003-0349-7

Source DB:  PubMed          Journal:  Langenbecks Arch Surg        ISSN: 1435-2443            Impact factor:   3.445


  22 in total

1.  Prospective evaluation of selective defunctioning stoma for low anterior resection with total mesorectal excision.

Authors:  R T Poon; K W Chu; J W Ho; C W Chan; W L Law; J Wong
Journal:  World J Surg       Date:  1999-05       Impact factor: 3.352

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Journal:  Br J Surg       Date:  1996-01       Impact factor: 6.939

3.  Risk factors for anastomotic leakage after low anterior resection with total mesorectal excision.

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Journal:  Am J Surg       Date:  2000-02       Impact factor: 2.565

Review 4.  Etiology and management of fecal incontinence.

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Journal:  Dis Colon Rectum       Date:  1993-01       Impact factor: 4.585

5.  Anastomotic leakage after colorectal cancer surgery: a risk factor for recurrence and poor prognosis.

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Journal:  Jpn J Clin Oncol       Date:  1993-10       Impact factor: 3.019

6.  Influence of a defunctioning stoma on leakage rates after low colorectal anastomosis and colonic J pouch-anal anastomosis.

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Journal:  Br J Surg       Date:  1998-08       Impact factor: 6.939

7.  Anastomotic leaks in colorectal cancer surgery: a risk factor for recurrence?

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Journal:  Int J Colorectal Dis       Date:  1991-11       Impact factor: 2.571

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Journal:  Int J Colorectal Dis       Date:  1991-05       Impact factor: 2.571

Review 9.  Early infective complications and late recurrent cancer in stapled colonic anastomoses.

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Journal:  Dis Colon Rectum       Date:  1989-01       Impact factor: 4.585

10.  Locoregional recurrence in patients with anastomotic leakage after anterior resection for rectal carcinoma.

Authors:  S Merkel; W Y Wang; O Schmidt; O Dworak; C Wittekind; W Hohenberger; P Hermanek
Journal:  Colorectal Dis       Date:  2001-05       Impact factor: 3.788

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  13 in total

1.  Diverting stoma with anterior resection for rectal cancer: does it reduce overall anastomotic leakage and leaks requiring laparotomy?

Authors:  Zhi-Jie Cong; Liang-Hao Hu; Ming Zhong; Lu Chen
Journal:  Int J Clin Exp Med       Date:  2015-08-15

2.  Quality management in rectal carcinoma: what is feasible?

Authors:  Susanne Merkel; Daniela Klossek; Jonas Göhl; Thomas Papadopoulos; Werner Hohenberger; Paul Hermanek
Journal:  Int J Colorectal Dis       Date:  2009-06-02       Impact factor: 2.571

Review 3.  Low anterior resection syndrome (LARS): cause and effect and reconstructive considerations.

Authors:  Y Ziv; A Zbar; Y Bar-Shavit; I Igov
Journal:  Tech Coloproctol       Date:  2012-10-18       Impact factor: 3.781

4.  The Impact of Anastomotic Leakage on Anal Function Following Intersphincteric Resection.

Authors:  Mitsuru Yokota; Masaaki Ito; Yuji Nishizawa; Akihiro Kobayashi; Norio Saito
Journal:  World J Surg       Date:  2017-08       Impact factor: 3.352

5.  Pelvic organ function and quality of life after anastomotic leakage following rectal cancer surgery.

Authors:  Stefan Riss; Stefan Stremitzer; Katharina Riss; Martina Mittlböck; Michael Bergmann; Anton Stift
Journal:  Wien Klin Wochenschr       Date:  2011-01-03       Impact factor: 1.704

6.  Outcomes of asymptomatic anastomotic leaks found on routine postoperative water-soluble enema following anterior resection for cancer.

Authors:  S Killeen; P Souroullas; H Ho Tin; I A Hunter; H O'Grady; J Gunn; J E Hartley
Journal:  World J Surg       Date:  2013-11       Impact factor: 3.352

7.  Does anastomotic leakage impair functional results and quality of life after laparoscopic sphincter-saving total mesorectal excision for rectal cancer? A case-matched study.

Authors:  Cécile Mongin; Léon Maggiori; Julie Agostini; Marianne Ferron; Yves Panis
Journal:  Int J Colorectal Dis       Date:  2014-01-31       Impact factor: 2.571

8.  Low anterior resection syndrome: a survey of the members of the American Society of Colon and Rectal Surgeons (ASCRS), the Spanish Association of Surgeons (AEC), and the Spanish Society of Coloproctology (AECP).

Authors:  Luis Miguel Jimenez-Gomez; Eloy Espin-Basany; Marc Marti-Gallostra; Jose Luis Sanchez-Garcia; Francesc Vallribera-Valls; Manuel Armengol-Carrasco
Journal:  Int J Colorectal Dis       Date:  2016-01-29       Impact factor: 2.571

9.  Predictors of fecal incontinence and related quality of life after a total mesorectal excision with primary anastomosis for patients with rectal cancer.

Authors:  Marieke S Walma; Verena N N Kornmann; Djamila Boerma; Marnix A J de Roos; Henderik L van Westreenen
Journal:  Ann Coloproctol       Date:  2015-02-28

10.  Systematic review of anastomotic leakage rate according to an international grading system following anterior resection for rectal cancer.

Authors:  Zhi-Jie Cong; Liang-Hao Hu; Zheng-Qian Bian; Guang-Yao Ye; Min-Hao Yu; Yun-He Gao; Zhao-Shen Li; En-Da Yu; Ming Zhong
Journal:  PLoS One       Date:  2013-09-25       Impact factor: 3.240

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