Literature DB >> 23982778

Outcomes of asymptomatic anastomotic leaks found on routine postoperative water-soluble enema following anterior resection for cancer.

S Killeen1, P Souroullas, H Ho Tin, I A Hunter, H O'Grady, J Gunn, J E Hartley.   

Abstract

BACKGROUND: The incidence and consequence of an anastomotic leak associated with low anterior resection for cancer mandates covering stoma in most cases. A water-soluble enema is often performed to assess anastomotic integrity prior to stoma reversal. The functional outcome following reversal in patients with occult radiologically detected leaks is poorly defined. The goal of the present study was to determine the functional outcome in patients with a radiologically detected anastomotic leak who subsequently underwent stoma reversal.
METHODS: This case control study used patients with and without radiologically detected occult anastomotic leak having undergone reversal of covering stomata. The study group was matched with controls for age, gender, procedure, tumor stage, and adjuvant/neoadjuvant therapy. Validated fecal incontinence quality of life (FIQL), Cleveland Clinic Fecal Incontinence Score (CCFIS), and the Memorial Sloan-Kettering Cancer Center (MSKCC) Bowel Function Index (BFI) were used. Patient satisfaction, medication use, and ancillary procedures prior to closure were also recorded.
RESULTS: Thirteen patients with radiologically detected occult anastomotic leaks and 13 matched controls were identified from a prospectively maintained database. The FIQL, CCFIS, and MSKCC BFI scores were significantly reduced in those with occult leaks. The mean number of radiological and surgical interventions was significantly greater in the patients with occult leaks. Antidiarrheal and bulking agent use, as well as patient satisfaction, were the same for both groups. Only one patient in the occult leak group would not undergo stoma reversal again.
CONCLUSIONS: Reversal of a defunctioning ileostomy in the presence of an occult radiological leak can be associated with poorer functional outcomes, but patient satisfaction is undiminished.

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Year:  2013        PMID: 23982778     DOI: 10.1007/s00268-013-2193-4

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  21 in total

1.  The persisting presacral sinus after anastomotic leakage following anterior resection or restorative proctocolectomy.

Authors:  P J van Koperen; E S van der Zaag; J M T Omloo; J F M Slors; W A Bemelman
Journal:  Colorectal Dis       Date:  2011-01       Impact factor: 3.788

2.  Anastomotic leakage and functional outcome after anterior resection of the rectum.

Authors:  O Hallböök; R Sjödahl
Journal:  Br J Surg       Date:  1996-01       Impact factor: 6.939

3.  Risk factors and clinical outcome for anastomotic leakage after total mesorectal excision for rectal cancer.

Authors:  Won-Suk Lee; Seong Hyeon Yun; Young-Nam Roh; Hae-Ran Yun; Woo Yong Lee; Yong Beom Cho; Ho-Kyung Chun
Journal:  World J Surg       Date:  2008-06       Impact factor: 3.352

4.  Quality of life, functional outcome, and complications of coloplasty pouch after low anterior resection.

Authors:  Feza H Remzi; Victor W Fazio; Emre Gorgun; Massarat Zutshi; James M Church; Ian C Lavery; Tracy L Hull
Journal:  Dis Colon Rectum       Date:  2005-04       Impact factor: 4.585

5.  Does anastomotic leakage affect functional outcome after rectal resection for cancer?

Authors:  Birgit Bittorf; Uwe Stadelmaier; Susanne Merkel; Werner Hohenberger; Klaus E Matzel
Journal:  Langenbecks Arch Surg       Date:  2003-02-07       Impact factor: 3.445

6.  Symptomatic anastomotic leakage diagnosed after hospital discharge following low anterior resection for rectal cancer.

Authors:  P Matthiessen; R Lindgren; O Hallböök; J Rutegård; R Sjödahl
Journal:  Colorectal Dis       Date:  2009-07-07       Impact factor: 3.788

7.  Consequences of anastomotic leak after restorative proctectomy for cancer: effect on long-term function and quality of life.

Authors:  Jean H Ashburn; Luca Stocchi; Ravi P Kiran; David W Dietz; Feza H Remzi
Journal:  Dis Colon Rectum       Date:  2013-03       Impact factor: 4.585

8.  Anastomotic leakage after curative anterior resection for rectal cancer: short and long-term outcome.

Authors:  C A Bertelsen; A H Andreasen; T Jørgensen; H Harling
Journal:  Colorectal Dis       Date:  2009-04-29       Impact factor: 3.788

9.  A diverting stoma is not necessary when performing a handsewn coloanal anastomosis for lower rectal cancer.

Authors:  Jung Wook Huh; Yoon Ah Park; Seung Kook Sohn
Journal:  Dis Colon Rectum       Date:  2007-07       Impact factor: 4.585

10.  The Dutch multicenter experience of the endo-sponge treatment for anastomotic leakage after colorectal surgery.

Authors:  P J van Koperen; M I van Berge Henegouwen; C Rosman; C M Bakker; P Heres; J F M Slors; W A Bemelman
Journal:  Surg Endosc       Date:  2008-11-27       Impact factor: 4.584

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  4 in total

Review 1.  Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage.

Authors:  Sami A Chadi; Abe Fingerhut; Mariana Berho; Steven R DeMeester; James W Fleshman; Neil H Hyman; David A Margolin; Joseph E Martz; Elisabeth C McLemore; Daniela Molena; Martin I Newman; Janice F Rafferty; Bashar Safar; Anthony J Senagore; Oded Zmora; Steven D Wexner
Journal:  J Gastrointest Surg       Date:  2016-09-16       Impact factor: 3.452

Review 2.  Utility of contrast enema to assess anastomotic integrity and the natural history of radiological leaks after low rectal surgery: systematic review and meta-analysis.

Authors:  K Habib; A Gupta; D White; Fayyaz A K Mazari; T R Wilson
Journal:  Int J Colorectal Dis       Date:  2015-04-29       Impact factor: 2.571

3.  Is water-soluble contrast enema examination for integrity of rectal anastomosis necessary prior to ileostomy reversal?

Authors:  Hui Lu Goh; Lauren Hawkins; Sivesh K Kamarajah; Sharad Karandikar; Mark Goldstein
Journal:  JGH Open       Date:  2019-11-06

Review 4.  Less is more-the best test for anastomotic leaks in rectal cancer patients prior to ileostomy reversal.

Authors:  Flavius Sandra-Petrescu; Florian Herrle; Simon Lindner; Steffen Eitelbuss; Svetlana Hetjens; Joshua Gawlitza; Julia Hardt; Steffen Seyfried; Christian Galata; Christoph Reissfelder
Journal:  Int J Colorectal Dis       Date:  2021-07-12       Impact factor: 2.571

  4 in total

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