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Literature DB >> 12584449

Cloning and mapping of platypus SOX2 and SOX14: insights into SOX group B evolution.

P J Kirby¹, P D Waters, M Delbridge, M Svartman, A N Stewart, K Nagai, J A M Graves.

Abstract

Group B SOX genes, the closest relatives to the sex-determining gene SRY, are thought to have evolved from a single ancestral SOX B by a series of duplications and translocations. The two SOX B genes SOX2 and SOX14 co-localize to chromosome 3q in humans. SOX2 and SOX14 homologues were cloned and characterized in the platypus, a monotreme mammal distantly related to man. The two genes were found to co-localize to chromosome 1q in this species. Proximity of the two related genes has therefore been conserved for 170 Myr, since humans and platypus diverged. The sequence similarity and conserved synteny of these group B genes provide clues to their origin. A simple model of SOX group B gene evolution is proposed. Copyright 2002 S. Karger AG, Basel

Entities: Gene Species

Mesh：

Substances：

Year: 2002 PMID： 12584449 DOI： 10.1159/000068539

Source DB: PubMed Journal: Cytogenet Genome Res ISSN： 1424-8581 Impact factor: 1.636

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Cited

14 in total

1. Comparative cytogenetic mapping of Sox2 and Sox14 in cichlid fishes and inferences on the genomic organization of both genes in vertebrates.

Authors: Juliana Mazzuchelli; Fengtang Yang; Thomas D Kocher; Cesar Martins
Journal: Chromosome Res Date: 2011-06-21 Impact factor: 5.239

2. Remarkable evolutionary conservation of SOX14 orthologues.

Authors: Jelena Popovic; Milena Stevanovic
Journal: J Genet Date: 2009-04 Impact factor: 1.166

3. Sex determination in platypus and echidna: autosomal location of SOX3 confirms the absence of SRY from monotremes.

Authors: M C Wallis; P D Waters; M L Delbridge; P J Kirby; A J Pask; F Grützner; W Rens; M A Ferguson-Smith; J A M Graves
Journal: Chromosome Res Date: 2008-01-09 Impact factor: 5.239

4. Characterizing the chromosomes of the platypus (Ornithorhynchus anatinus).

Authors: Daniel McMillan; Pat Miethke; Amber E Alsop; Willem Rens; Patricia O'Brien; Vladimir Trifonov; Frederic Veyrunes; Kyriena Schatzkamer; Colin L Kremitzki; Tina Graves; Wesley Warren; Frank Grützner; Malcolm A Ferguson-Smith; Jennifer A Marshall Graves
Journal: Chromosome Res Date: 2008-01-09 Impact factor: 5.239

Review 10. Evolution of non-coding regulatory sequences involved in the developmental process: reflection of differential employment of paralogous genes as highlighted by Sox2 and group B1 Sox genes.

Authors: Yusuke Kamachi; Makiko Iwafuchi; Yuichi Okuda; Tatsuya Takemoto; Masanori Uchikawa; Hisato Kondoh
Journal: Proc Jpn Acad Ser B Phys Biol Sci Date: 2009 Impact factor: 3.493

Cloning and mapping of platypus SOX2 and SOX14: insights into SOX group B evolution.

1. Comparative cytogenetic mapping of Sox2 and Sox14 in cichlid fishes and inferences on the genomic organization of both genes in vertebrates.

2. Remarkable evolutionary conservation of SOX14 orthologues.

3. Sex determination in platypus and echidna: autosomal location of SOX3 confirms the absence of SRY from monotremes.

4. Characterizing the chromosomes of the platypus (Ornithorhynchus anatinus).

5. Application of a novel strategy of engineering conditional alleles to a single exon gene, Sox2.

6. Copy number variation in the porcine genome inferred from a 60 k SNP BeadChip.

Review 7. Sex determination strategies in 2012: towards a common regulatory model?

8. Conserved genomic organisation of Group B Sox genes in insects.

9. Molecular patterns of sex determination in the animal kingdom: a comparative study of the biology of reproduction.

Review 10. Evolution of non-coding regulatory sequences involved in the developmental process: reflection of differential employment of paralogous genes as highlighted by Sox2 and group B1 Sox genes.