OBJECTIVES: Cyclic congestion and decongestion in the two nasal cavities is seen in connection with the respiratory function of the nose. The turbulent behavior of nasal airflow is a prerequisite for adequate contact of inspired air particles with the mucosa. The aim of this study was to gain insight into this turbulent behavior of nasal airflow during the nasal cycle. METHODS: The nasal cycle in 10 healthy human subjects was investigated using endoscopic imaging, rhinoresistometry, and acoustic rhinometry every 20 minutes over a time period of up to 15 hours. The following parameters were recorded for each nasal cavity: airflow resistance, hydraulic diameter, friction coefficient lambda as an indicator for the wall configuration triggering turbulence, transition from laminar to turbulent flow, and the minimal cross-sectional areas. RESULTS: In addition to the known cyclic change of flow resistance and nasal width, a periodic change in the turbulence behavior was observed. In the resting phase, mainly laminar flow was found. During the working phase, the onset of turbulence occurred already at low flow velocities. The increase of turbulence during the working phase is caused by the increase in cross-sectional area in the anterior cavum due to decongestion of the mucosa of the head of the inferior turbinate and the septal tuberculum. CONCLUSIONS: Rhinoresistometry and acoustic rhinometry complement each other. The combination of the two methods provides insight into the functional changes during the nasal cycle and into nasal physiology in general. The authors therefore advocate a combination of the two methods for functional evaluation of the nasal airway.
OBJECTIVES: Cyclic congestion and decongestion in the two nasal cavities is seen in connection with the respiratory function of the nose. The turbulent behavior of nasal airflow is a prerequisite for adequate contact of inspired air particles with the mucosa. The aim of this study was to gain insight into this turbulent behavior of nasal airflow during the nasal cycle. METHODS: The nasal cycle in 10 healthy human subjects was investigated using endoscopic imaging, rhinoresistometry, and acoustic rhinometry every 20 minutes over a time period of up to 15 hours. The following parameters were recorded for each nasal cavity: airflow resistance, hydraulic diameter, friction coefficient lambda as an indicator for the wall configuration triggering turbulence, transition from laminar to turbulent flow, and the minimal cross-sectional areas. RESULTS: In addition to the known cyclic change of flow resistance and nasal width, a periodic change in the turbulence behavior was observed. In the resting phase, mainly laminar flow was found. During the working phase, the onset of turbulence occurred already at low flow velocities. The increase of turbulence during the working phase is caused by the increase in cross-sectional area in the anterior cavum due to decongestion of the mucosa of the head of the inferior turbinate and the septal tuberculum. CONCLUSIONS: Rhinoresistometry and acoustic rhinometry complement each other. The combination of the two methods provides insight into the functional changes during the nasal cycle and into nasal physiology in general. The authors therefore advocate a combination of the two methods for functional evaluation of the nasal airway.
Authors: Ross L Walenga; P Worth Longest; Anubhav Kaviratna; Michael Hindle Journal: J Aerosol Med Pulm Drug Deliv Date: 2017-01-11 Impact factor: 2.849
Authors: Ruchin G Patel; Guilherme J M Garcia; Dennis O Frank-Ito; Julia S Kimbell; John S Rhee Journal: Otolaryngol Head Neck Surg Date: 2014-12-01 Impact factor: 3.497
Authors: Scott Shadfar; William W Shockley; Gita M Fleischman; Anand R Dugar; Kibwei A McKinney; Dennis O Frank-Ito; Julia S Kimbell Journal: JAMA Facial Plast Surg Date: 2014 Sep-Oct Impact factor: 4.611
Authors: Dennis O Frank-Ito; Julia S Kimbell; Azadeh A T Borojeni; Guilherme J M Garcia; John S Rhee Journal: Clin Biomech (Bristol, Avon) Date: 2018-12-19 Impact factor: 2.063