Literature DB >> 12531877

Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood.

Jacqueline D Trudeau1, Carolyn Kelly-Smith, C Bruce Verchere, John F Elliott, Jan P Dutz, Diane T Finegood, Pere Santamaria, Rusung Tan.   

Abstract

Autoimmune (type 1) diabetes mellitus results from the destruction of insulin-producing pancreatic beta cells by T lymphocytes. Prediction of cell-mediated autoimmune diseases by direct detection of autoreactive T cells in peripheral blood has proved elusive, in part because of their low frequency and reduced avidity for peptide MHC ligands. This article was published online in advance of the print edition. The date of publication is available from the JCI website, http://www.jci.org.

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Year:  2003        PMID: 12531877      PMCID: PMC151866          DOI: 10.1172/JCI16409

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


  32 in total

1.  Expansion of the antigenic repertoire of a single T cell receptor upon T cell activation.

Authors:  A Amrani; P Serra; J Yamanouchi; J D Trudeau; R Tan; J F Elliott; P Santamaria
Journal:  J Immunol       Date:  2001-07-15       Impact factor: 5.422

2.  Detection of glutamic acid decarboxylase-activated T cells with I-Ag7 tetramers.

Authors:  C P Liu; K Jiang; C H Wu; W H Lee; W J Lin
Journal:  Proc Natl Acad Sci U S A       Date:  2000-12-19       Impact factor: 11.205

Review 3.  Modern concepts for the prediction of type 1 diabetes.

Authors:  J Seissler; E Hatziagelaki; W A Scherbaum
Journal:  Exp Clin Endocrinol Diabetes       Date:  2001       Impact factor: 2.949

Review 4.  Insulin-dependent diabetes mellitus.

Authors:  R Tisch; H McDevitt
Journal:  Cell       Date:  1996-05-03       Impact factor: 41.582

5.  Identification of type II collagen peptide 261-273-specific T cell clones in a patient with relapsing polychondritis.

Authors:  Jane H Buckner; Megan Van Landeghen; William W Kwok; Laura Tsarknaridis
Journal:  Arthritis Rheum       Date:  2002-01

Review 6.  International Workshop on Lessons From Animal Models for Human Type 1 Diabetes: identification of insulin but not glutamic acid decarboxylase or IA-2 as specific autoantigens of humoral autoimmunity in nonobese diabetic mice.

Authors:  E Bonifacio; M Atkinson; G Eisenbarth; D Serreze; T W Kay; E Lee-Chan; B Singh
Journal:  Diabetes       Date:  2001-11       Impact factor: 9.461

7.  Progression of autoimmune diabetes driven by avidity maturation of a T-cell population.

Authors:  A Amrani; J Verdaguer; P Serra; S Tafuro; R Tan; P Santamaria
Journal:  Nature       Date:  2000-08-17       Impact factor: 49.962

8.  Lack of autoimmune serological reactions in rodent models of insulin dependent diabetes mellitus.

Authors:  I R Mackay; A Bone; T Tuomi; R Elliott; T Mandel; C Karopoulos; M J Rowley
Journal:  J Autoimmun       Date:  1996-12       Impact factor: 7.094

9.  Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes.

Authors:  L S Wicker; E H Leiter; J A Todd; R J Renjilian; E Peterson; P A Fischer; P L Podolin; M Zijlstra; R Jaenisch; L B Peterson
Journal:  Diabetes       Date:  1994-03       Impact factor: 9.461

Review 10.  Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention.

Authors:  Roland S Liblau; F Susan Wong; Lennart T Mars; Pere Santamaria
Journal:  Immunity       Date:  2002-07       Impact factor: 31.745

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  91 in total

1.  Enumerating autoreactive T cells in peripheral blood: a big step in diabetes prediction.

Authors:  George S Eisenbarth; Brian L Kotzin
Journal:  J Clin Invest       Date:  2003-01       Impact factor: 14.808

2.  A pancreatic beta-cell-specific homolog of glucose-6-phosphatase emerges as a major target of cell-mediated autoimmunity in diabetes.

Authors:  John C Hutton; George S Eisenbarth
Journal:  Proc Natl Acad Sci U S A       Date:  2003-07-14       Impact factor: 11.205

Review 3.  Effector lymphocytes in islet cell autoimmunity.

Authors:  Pere Santamaria
Journal:  Rev Endocr Metab Disord       Date:  2003-09       Impact factor: 6.514

4.  The pathogenicity of self-antigen decreases at high levels of autoantigenicity: a computational approach.

Authors:  Anmar Khadra; Pere Santamaria; Leah Edelstein-Keshet
Journal:  Int Immunol       Date:  2010-05-24       Impact factor: 4.823

5.  Beta cells under attack: toward a better understanding of type 1 diabetes immunopathology.

Authors:  Ken T Coppieters; Bart O Roep; Matthias G von Herrath
Journal:  Semin Immunopathol       Date:  2010-12-18       Impact factor: 9.623

6.  Pathogenesis of NOD diabetes is initiated by reactivity to the insulin B chain 9-23 epitope and involves functional epitope spreading.

Authors:  Suchitra Prasad; Adam P Kohm; Jeffrey S McMahon; Xunrong Luo; Stephen D Miller
Journal:  J Autoimmun       Date:  2012-05-28       Impact factor: 7.094

Review 7.  T cell epitopes and post-translationally modified epitopes in type 1 diabetes.

Authors:  John W McGinty; Meghan L Marré; Veronique Bajzik; Jon D Piganelli; Eddie A James
Journal:  Curr Diab Rep       Date:  2015-11       Impact factor: 4.810

8.  Biomarkers for type 1 diabetes.

Authors:  Sharad Purohit; Jin-Xiong She
Journal:  Int J Clin Exp Med       Date:  2008-02-29

9.  The CD137 Ligand Is Important for Type 1 Diabetes Development but Dispensable for the Homeostasis of Disease-Suppressive CD137+ FOXP3+ Regulatory CD4 T Cells.

Authors:  Bardees M Foda; Ashley E Ciecko; David V Serreze; William M Ridgway; Aron M Geurts; Yi-Guang Chen
Journal:  J Immunol       Date:  2020-04-15       Impact factor: 5.422

10.  Pre-existing autoimmunity determines type 1 diabetes outcome after Flt3-ligand treatment.

Authors:  Tom L Van Belle; Therese Juntti; Jeanette Liao; Matthias G von Herrath
Journal:  J Autoimmun       Date:  2009-12-09       Impact factor: 7.094

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