Literature DB >> 12861077

A pancreatic beta-cell-specific homolog of glucose-6-phosphatase emerges as a major target of cell-mediated autoimmunity in diabetes.

John C Hutton1, George S Eisenbarth.   

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Year:  2003        PMID: 12861077      PMCID: PMC166361          DOI: 10.1073/pnas.1633447100

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


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  30 in total

1.  Expansion of the antigenic repertoire of a single T cell receptor upon T cell activation.

Authors:  A Amrani; P Serra; J Yamanouchi; J D Trudeau; R Tan; J F Elliott; P Santamaria
Journal:  J Immunol       Date:  2001-07-15       Impact factor: 5.422

2.  Transient insulin autoantibody expression independent of development of diabetes: comparison of NOD and NOR strains.

Authors:  N Abiru; L Yu; D Miao; A K Maniatis; E Liu; H Moriyama; G S Eisenbarth
Journal:  J Autoimmun       Date:  2001-08       Impact factor: 7.094

3.  Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease.

Authors:  Hironori Ueda; Joanna M M Howson; Laura Esposito; Joanne Heward; Hywel Snook; Giselle Chamberlain; Daniel B Rainbow; Kara M D Hunter; Annabel N Smith; Gianfranco Di Genova; Mathias H Herr; Ingrid Dahlman; Felicity Payne; Deborah Smyth; Christopher Lowe; Rebecca C J Twells; Sarah Howlett; Barry Healy; Sarah Nutland; Helen E Rance; Vin Everett; Luc J Smink; Alex C Lam; Heather J Cordell; Neil M Walker; Cristina Bordin; John Hulme; Costantino Motzo; Francesco Cucca; J Fred Hess; Michael L Metzker; Jane Rogers; Simon Gregory; Amit Allahabadia; Ratnasingam Nithiyananthan; Eva Tuomilehto-Wolf; Jaakko Tuomilehto; Polly Bingley; Kathleen M Gillespie; Dag E Undlien; Kjersti S Rønningen; Cristian Guja; Constantin Ionescu-Tîrgovişte; David A Savage; A Peter Maxwell; Dennis J Carson; Chris C Patterson; Jayne A Franklyn; David G Clayton; Laurence B Peterson; Linda S Wicker; John A Todd; Stephen C L Gough
Journal:  Nature       Date:  2003-04-30       Impact factor: 49.962

4.  Prediction of spontaneous autoimmune diabetes in NOD mice by quantification of autoreactive T cells in peripheral blood.

Authors:  Jacqueline D Trudeau; Carolyn Kelly-Smith; C Bruce Verchere; John F Elliott; Jan P Dutz; Diane T Finegood; Pere Santamaria; Rusung Tan
Journal:  J Clin Invest       Date:  2003-01       Impact factor: 14.808

5.  T-lymphocyte clone specific for pancreatic islet antigen.

Authors:  K Haskins; M Portas; B Bradley; D Wegmann; K Lafferty
Journal:  Diabetes       Date:  1988-10       Impact factor: 9.461

6.  T-cell epitope analysis on the autoantigen phogrin (IA-2beta) in the nonobese diabetic mouse.

Authors:  K Kelemen; D R Wegmann; J C Hutton
Journal:  Diabetes       Date:  2001-08       Impact factor: 9.461

7.  Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes.

Authors:  C C Martin; L J Bischof; B Bergman; L A Hornbuckle; C Hilliker; C Frigeri; D Wahl; C A Svitek; R Wong; J K Goldman; J K Oeser; F Leprêtre; P Froguel; R M O'Brien; J C Hutton
Journal:  J Biol Chem       Date:  2001-04-10       Impact factor: 5.157

8.  Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice.

Authors:  Michele P Marron; Robert T Graser; Harold D Chapman; David V Serreze
Journal:  Proc Natl Acad Sci U S A       Date:  2002-10-02       Impact factor: 11.205

9.  T cell response to preproinsulin I and II in the nonobese diabetic mouse.

Authors:  Philippe Halbout; Jean-Paul Briand; Chantal Bécourt; Sylviane Muller; Christian Boitard
Journal:  J Immunol       Date:  2002-09-01       Impact factor: 5.422

10.  Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

Authors:  Scott M Lieberman; Anne M Evans; Bingye Han; Toshiyuki Takaki; Yuliya Vinnitskaya; Jennifer A Caldwell; David V Serreze; Jeffrey Shabanowitz; Donald F Hunt; Stanley G Nathenson; Pere Santamaria; Teresa P DiLorenzo
Journal:  Proc Natl Acad Sci U S A       Date:  2003-06-18       Impact factor: 12.779

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  14 in total

Review 1.  Cellular therapies for type 1 diabetes.

Authors:  D D Lee; E Grossman; A S Chong
Journal:  Horm Metab Res       Date:  2008-02       Impact factor: 2.936

Review 2.  Immunologic endocrine disorders.

Authors:  Aaron W Michels; George S Eisenbarth
Journal:  J Allergy Clin Immunol       Date:  2010-02       Impact factor: 10.793

Review 3.  Autoimmune polyglandular syndromes.

Authors:  Aaron W Michels; Peter A Gottlieb
Journal:  Nat Rev Endocrinol       Date:  2010-03-23       Impact factor: 43.330

4.  G6PC2 Modulates the Effects of Dexamethasone on Fasting Blood Glucose and Glucose Tolerance.

Authors:  Kayla A Boortz; Kristen E Syring; Rebecca A Lee; Chunhua Dai; James K Oeser; Owen P McGuinness; Jen-Chywan Wang; Richard M O'Brien
Journal:  Endocrinology       Date:  2016-09-21       Impact factor: 4.736

5.  Multiple functional polymorphisms in the G6PC2 gene contribute to the association with higher fasting plasma glucose levels.

Authors:  D A Baerenwald; A Bonnefond; N Bouatia-Naji; B P Flemming; O C Umunakwe; J K Oeser; L D Pound; N L Conley; S Cauchi; S Lobbens; E Eury; B Balkau; O Lantieri; P K Dadi; D A Jacobson; P Froguel; R M O'Brien
Journal:  Diabetologia       Date:  2013-03-19       Impact factor: 10.122

6.  Moving on from GWAS: functional studies on the G6PC2 gene implicated in the regulation of fasting blood glucose.

Authors:  Richard M O'Brien
Journal:  Curr Diab Rep       Date:  2013-12       Impact factor: 4.810

7.  Alternative splicing of G6PC2, the gene coding for the islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP), results in differential expression in human thymus and spleen compared with pancreas.

Authors:  R S Dogra; P Vaidyanathan; K R Prabakar; K E Marshall; J C Hutton; A Pugliese
Journal:  Diabetologia       Date:  2006-03-07       Impact factor: 10.122

8.  Foxa2 and MafA regulate islet-specific glucose-6-phosphatase catalytic subunit-related protein gene expression.

Authors:  Cyrus C Martin; Brian P Flemming; Yingda Wang; James K Oeser; Richard M O'Brien
Journal:  J Mol Endocrinol       Date:  2008-08-27       Impact factor: 5.098

9.  Pancreatic islet beta cell-specific deletion of G6pc2 reduces fasting blood glucose.

Authors:  Karin J Bosma; Mohsin Rahim; Kritika Singh; Slavina B Goleva; Martha L Wall; Jing Xia; Kristen E Syring; James K Oeser; Greg Poffenberger; Owen P McGuinness; Anna L Means; Alvin C Powers; Wen-Hong Li; Lea K Davis; Jamey D Young; Richard M O'Brien
Journal:  J Mol Endocrinol       Date:  2020-05       Impact factor: 5.098

10.  Genetic and functional assessment of the role of the rs13431652-A and rs573225-A alleles in the G6PC2 promoter that are strongly associated with elevated fasting glucose levels.

Authors:  Nabila Bouatia-Naji; Amélie Bonnefond; Devin A Baerenwald; Marion Marchand; Marco Bugliani; Piero Marchetti; François Pattou; Richard L Printz; Brian P Flemming; Obi C Umunakwe; Nicholas L Conley; Martine Vaxillaire; Olivier Lantieri; Beverley Balkau; Michel Marre; Claire Lévy-Marchal; Paul Elliott; Marjo-Riitta Jarvelin; David Meyre; Christian Dina; James K Oeser; Philippe Froguel; Richard M O'Brien
Journal:  Diabetes       Date:  2010-07-09       Impact factor: 9.461

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