Literature DB >> 12527759

Mutagenic potentials of damaged nucleic acids produced by reactive oxygen/nitrogen species: approaches using synthetic oligonucleotides and nucleotides: survey and summary.

Hiroyuki Kamiya1.   

Abstract

DNA and DNA precursors (deoxyribonucleotides) suffer damage by reactive oxygen/nitrogen species. They are important mutagens for organisms, due to their endogenous formation. Damaged DNA and nucleotides cause alterations of the genetic information by the mispairing properties of the damaged bases, such as 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) and 2-hydroxyadenine. Here, the author reviews the mutagenic potentials of damaged bases in DNA and of damaged DNA precursors formed by reactive oxygen/nitrogen species, focusing on the results obtained with synthetic oligonucleotides and 2'-deoxyribonucleoside 5'-triphosphates.

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Year:  2003        PMID： 12527759      PMCID： PMC140503          DOI： 10.1093/nar/gkg137

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  137 in total

1.  Enzymatic repair of 5-formyluracil. II. Mismatch formation between 5-formyluracil and guanine during dna replication and its recognition by two proteins involved in base excision repair (AlkA) and mismatch repair (MutS).

Authors:  H Terato; A Masaoka; M Kobayashi; S Fukushima; Y Ohyama; M Yoshida; H Ide
Journal:  J Biol Chem       Date:  1999-08-27       Impact factor: 5.157

2.  "Action-at-a-distance" mutagenesis. 8-oxo-7, 8-dihydro-2'-deoxyguanosine causes base substitution errors at neighboring template sites when copied by DNA polymerase beta.

Authors:  E Efrati; G Tocco; R Eritja; S H Wilson; M F Goodman
Journal:  J Biol Chem       Date:  1999-05-28       Impact factor: 5.157

3.  In vitro selection of sequence contexts which enhance bypass of abasic sites and tetrahydrofuran by T4 DNA polymerase holoenzyme.

Authors:  Z Hatahet; M Zhou; L J Reha-Krantz; H Ide; S W Morrical; S S Wallace
Journal:  J Mol Biol       Date:  1999-03-05       Impact factor: 5.469

4.  Comparison of the mutagenic properties of 8-oxo-7,8-dihydro-2'-deoxyadenosine and 8-oxo-7,8-dihydro-2'-deoxyguanosine DNA lesions in mammalian cells.

Authors:  X Tan; A P Grollman; S Shibutani
Journal:  Carcinogenesis       Date:  1999-12       Impact factor: 4.944

5.  The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication.

Authors:  N B Reuven; G Arad; A Maor-Shoshani; Z Livneh
Journal:  J Biol Chem       Date:  1999-11-05       Impact factor: 5.157

6.  Role of iron and superoxide for generation of hydroxyl radical, oxidative DNA lesions, and mutagenesis in Escherichia coli.

Authors:  T Nunoshiba; F Obata; A C Boss; S Oikawa; T Mori; S Kawanishi; K Yamamoto
Journal:  J Biol Chem       Date:  1999-12-03       Impact factor: 5.157

7.  Formation of 5-formyl-2'-deoxycytidine from 5-methyl-2'-deoxycytidine in duplex DNA by Fenton-type reactions and gamma-irradiation.

Authors:  N Murata-Kamiya; H Kamiya; N Karino; Y Ueno; H Kaji; A Matsuda; H Kasai
Journal:  Nucleic Acids Res       Date:  1999-11-15       Impact factor: 16.971

8.  Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues.

Authors:  J Nakamura; J A Swenberg
Journal:  Cancer Res       Date:  1999-06-01       Impact factor: 12.701

9.  UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V.

Authors:  M Tang; X Shen; E G Frank; M O'Donnell; R Woodgate; M F Goodman
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

10.  The oxidized forms of dATP are substrates for the human MutT homologue, the hMTH1 protein.

Authors:  K Fujikawa; H Kamiya; H Yakushiji; Y Fujii; Y Nakabeppu; H Kasai
Journal:  J Biol Chem       Date:  1999-06-25       Impact factor: 5.157
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  78 in total

1.  Direct analysis in real time (DART) mass spectrometry of nucleotides and nucleosides: elucidation of a novel fragment [C5H5O]+ and its in-source adducts.

Authors:  Matthew Curtis; Mikael A Minier; Priyanka Chitranshi; O David Sparkman; Patrick R Jones; Liang Xue
Journal:  J Am Soc Mass Spectrom       Date:  2010-04-07       Impact factor: 3.109

2.  Expression, purification, crystallization and preliminary X-ray characterization of two crystal forms of stationary-phase survival E protein from Campylobacter jejuni.

Authors:  A M D Gonçalves; A T Rêgo; M Thomaz; F J Enguita; M A Carrondo
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2008-02-29

3.  Facile quantification of lesions derived from 2'-deoxyguanosine in DNA.

Authors:  Liang Xue; Marc M Greenberg
Journal:  J Am Chem Soc       Date:  2007-05-11       Impact factor: 15.419

4.  How does modification of adenine by hydroxyl radical influence the stability and the nature of stacking interactions in adenine-cytosine complex?

Authors:  Zaneta Czyznikowska
Journal:  J Mol Model       Date:  2009-02-07       Impact factor: 1.810

Review 5.  DNA adducts: Formation, biological effects, and new biospecimens for mass spectrometric measurements in humans.

Authors:  Byeong Hwa Yun; Jingshu Guo; Medjda Bellamri; Robert J Turesky
Journal:  Mass Spectrom Rev       Date:  2018-06-11       Impact factor: 10.946

6.  Functional study of the P32T ITPA variant associated with drug sensitivity in humans.

Authors:  Elena I Stepchenkova; Elena R Tarakhovskaya; Kathryn Spitler; Christin Frahm; Miriam R Menezes; Peter D Simone; Carol Kolar; Luis A Marky; Gloria E O Borgstahl; Youri I Pavlov
Journal:  J Mol Biol       Date:  2009-07-23       Impact factor: 5.469

7.  Mutagenic effects of 2-hydroxy-dATP on replication in a HeLa extract: induction of substitution and deletion mutations.

Authors:  Kazuya Satou; Hideyoshi Harashima; Hiroyuki Kamiya
Journal:  Nucleic Acids Res       Date:  2003-05-15       Impact factor: 16.971

8.  Adenine oxidation by pyrite-generated hydroxyl radicals.

Authors:  Corey A Cohn; Shawn C Fisher; Bruce J Brownawell; Martin Aa Schoonen
Journal:  Geochem Trans       Date:  2010-04-26       Impact factor: 4.737

9.  DNA polymerases as potential therapeutic targets for cancers deficient in the DNA mismatch repair proteins MSH2 or MLH1.

Authors:  Sarah A Martin; Nuala McCabe; Michelle Mullarkey; Robert Cummins; Darren J Burgess; Yusaku Nakabeppu; Sugako Oka; Elaine Kay; Christopher J Lord; Alan Ashworth
Journal:  Cancer Cell       Date:  2010-03-16       Impact factor: 31.743

10.  Experimental evidence indicating that mastreviruses probably did not co-diverge with their hosts.

Authors:  Gordon W Harkins; Wayne Delport; Siobain Duffy; Natasha Wood; Adérito L Monjane; Betty E Owor; Lara Donaldson; Salem Saumtally; Guy Triton; Rob W Briddon; Dionne N Shepherd; Edward P Rybicki; Darren P Martin; Arvind Varsani
Journal:  Virol J       Date:  2009-07-16       Impact factor: 4.099
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