Literature DB >> 12519989

ToxoDB: accessing the Toxoplasma gondii genome.

Jessica C Kissinger1, Bindu Gajria, Li Li, Ian T Paulsen, David S Roos.   

Abstract

ToxoDB (http://ToxoDB.org) provides a genome resource for the protozoan parasite Toxoplasma gondii. Several sequencing projects devoted to T. gondii have been completed or are in progress: an EST project (http://genome.wustl.edu/est/index.php?toxoplasma=1), a BAC clone end-sequencing project (http://www.sanger.ac.uk/Projects/T_gondii/) and an 8X random shotgun genomic sequencing project (http://www.tigr.org/tdb/e2k1/tga1/). ToxoDB was designed to provide a central point of access for all available T. gondii data, and a variety of data mining tools useful for the analysis of unfinished, un-annotated draft sequence during the early phases of the genome project. In later stages, as more and different types of data become available (microarray, proteomic, SNP, QTL, etc.) the database will provide an integrated data analysis platform facilitating user-defined queries across the different data types.

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Year:  2003        PMID: 12519989      PMCID: PMC165519          DOI: 10.1093/nar/gkg072

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  7 in total

1.  A relational schema for both array-based and SAGE gene expression experiments.

Authors:  C Stoeckert; A Pizarro; E Manduchi; M Gibson; B Brunk; J Crabtree; J Schug; S Shen-Orr; G C Overton
Journal:  Bioinformatics       Date:  2001-04       Impact factor: 6.937

2.  Construction of a molecular karyotype for Toxoplasma gondii.

Authors:  L D Sibley; J C Boothroyd
Journal:  Mol Biochem Parasitol       Date:  1992-04       Impact factor: 1.759

3.  PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished).

Authors:  Amit Bahl; Brian Brunk; Ross L Coppel; Jonathan Crabtree; Sharon J Diskin; Martin J Fraunholz; Gregory R Grant; Dinesh Gupta; Robert L Huestis; Jessica C Kissinger; Philip Labo; Li Li; Shannon K McWeeney; Arthur J Milgram; David S Roos; Jonathan Schug; Christian J Stoeckert
Journal:  Nucleic Acids Res       Date:  2002-01-01       Impact factor: 16.971

4.  The protozoan phylum Apicomplexa.

Authors:  J W Ajioka
Journal:  Methods       Date:  1997-10       Impact factor: 3.608

5.  Gene discovery by EST sequencing in Toxoplasma gondii reveals sequences restricted to the Apicomplexa.

Authors:  J W Ajioka; J C Boothroyd; B P Brunk; A Hehl; L Hillier; I D Manger; M Marra; G C Overton; D S Roos; K L Wan; R Waterston; L D Sibley
Journal:  Genome Res       Date:  1998-01       Impact factor: 9.043

6.  Gene discovery in Plasmodium chabaudi by genome survey sequencing.

Authors:  C S Janssen; M P Barrett; D Lawson; M A Quail; D Harris; S Bowman; R S Phillips; C M Turner
Journal:  Mol Biochem Parasitol       Date:  2001-04-06       Impact factor: 1.759

Review 7.  Toxoplasmic encephalitis in AIDS.

Authors:  B J Luft; J S Remington
Journal:  Clin Infect Dis       Date:  1992-08       Impact factor: 9.079

  7 in total
  75 in total

1.  ApiEST-DB: analyzing clustered EST data of the apicomplexan parasites.

Authors:  Li Li; Jonathan Crabtree; Steve Fischer; Deborah Pinney; Christian J Stoeckert; L David Sibley; David S Roos
Journal:  Nucleic Acids Res       Date:  2004-01-01       Impact factor: 16.971

Review 2.  Toxoplasma gondii: the model apicomplexan.

Authors:  Kami Kim; Louis M Weiss
Journal:  Int J Parasitol       Date:  2004-03-09       Impact factor: 3.981

3.  Parasite-specific eIF2 (eukaryotic initiation factor-2) kinase required for stress-induced translation control.

Authors:  William J Sullivan; Jana Narasimhan; Micah M Bhatti; Ronald C Wek
Journal:  Biochem J       Date:  2004-06-01       Impact factor: 3.857

4.  Extracellular Toxoplasma gondii tachyzoites metabolize and incorporate unnatural sugars into cellular proteins.

Authors:  Lidia A Nazarova; Roxanna J Ochoa; Krysten A Jones; Naomi S Morrissette; Jennifer A Prescher
Journal:  Microbes Infect       Date:  2015-12-11       Impact factor: 2.700

5.  A Toxoplasma gondii phosphoinositide phospholipase C (TgPI-PLC) with high affinity for phosphatidylinositol.

Authors:  Jianmin Fang; Norma Marchesini; Silvia N J Moreno
Journal:  Biochem J       Date:  2006-03-01       Impact factor: 3.857

6.  Histone-modifying complexes regulate gene expression pertinent to the differentiation of the protozoan parasite Toxoplasma gondii.

Authors:  Nehmé Saksouk; Micah M Bhatti; Sylvie Kieffer; Aaron T Smith; Karine Musset; Jérôme Garin; William J Sullivan; Marie-France Cesbron-Delauw; Mohamed-Ali Hakimi
Journal:  Mol Cell Biol       Date:  2005-12       Impact factor: 4.272

7.  Polymorphic secreted kinases are key virulence factors in toxoplasmosis.

Authors:  J P J Saeij; J P Boyle; S Coller; S Taylor; L D Sibley; E T Brooke-Powell; J W Ajioka; J C Boothroyd
Journal:  Science       Date:  2006-12-15       Impact factor: 47.728

8.  Host pathogen protein interactions predicted by comparative modeling.

Authors:  Fred P Davis; David T Barkan; Narayanan Eswar; James H McKerrow; Andrej Sali
Journal:  Protein Sci       Date:  2007-10-26       Impact factor: 6.725

9.  A novel GDP-dependent pyruvate kinase isozyme from Toxoplasma gondii localizes to both the apicoplast and the mitochondrion.

Authors:  Tomoya Saito; Manami Nishi; Muoy I Lim; Bo Wu; Takuya Maeda; Hisayuki Hashimoto; Tsutomu Takeuchi; David S Roos; Takashi Asai
Journal:  J Biol Chem       Date:  2008-03-06       Impact factor: 5.157

10.  CryptoDB: the Cryptosporidium genome resource.

Authors:  Daniela Puiu; Shinichiro Enomoto; Gregory A Buck; Mitchell S Abrahamsen; Jessica C Kissinger
Journal:  Nucleic Acids Res       Date:  2004-01-01       Impact factor: 16.971

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