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Literature DB >> 12519968

Human Gene-Centric Databases at the Weizmann Institute of Science: GeneCards, UDB, CroW 21 and HORDE.

Marilyn Safran¹, Vered Chalifa-Caspi, Orit Shmueli, Tsviya Olender, Michal Lapidot, Naomi Rosen, Michael Shmoish, Yakov Peter, Gustavo Glusman, Ester Feldmesser, Avital Adato, Inga Peter, Miriam Khen, Tal Atarot, Yoram Groner, Doron Lancet.

Abstract

Recent enhancements and current research in the GeneCards (GC) (http://bioinfo.weizmann.ac.il/cards/) project are described, including the addition of gene expression profiles and integrated gene locations. Also highlighted are the contributions of specialized associated human gene-centric databases developed at the Weizmann Institute. These include the Unified Database (UDB) (http://bioinfo.weizmann.ac.il/udb) for human genome mapping, the human Chromosome 21 database at the Weizmann Insti-tute (CroW 21) (http://bioinfo.weizmann.ac.il/crow21), and the Human Olfactory Receptor Data Explora-torium (HORDE) (http://bioinfo.weizmann.ac.il/HORDE). The synergistic relationships amongst these efforts have positively impacted the quality, quantity and usefulness of the GeneCards gene compendium.

Entities: Species

Mesh：

Substances：
Receptors, Odorant

Year: 2003 PMID： 12519968 PMCID： PMC165497 DOI： 10.1093/nar/gkg050

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

21 in total

1. Introducing RefSeq and LocusLink: curated human genome resources at the NCBI.

Authors: K D Pruitt; K S Katz; H Sicotte; D R Maglott
Journal: Trends Genet Date: 2000-01 Impact factor: 11.639

2. GESTALT: a workbench for automatic integration and visualization of large-scale genomic sequence analyses.

Authors: G Glusman; D Lancet
Journal: Bioinformatics Date: 2000-05 Impact factor: 6.937

3. GeneLynx: a gene-centric portal to the human genome.

Authors: B Lenhard; W S Hayes; W W Wasserman
Journal: Genome Res Date: 2001-12 Impact factor: 9.043

4. The Ensembl genome database project.

Authors: T Hubbard; D Barker; E Birney; G Cameron; Y Chen; L Clark; T Cox; J Cuff; V Curwen; T Down; R Durbin; E Eyras; J Gilbert; M Hammond; L Huminiecki; A Kasprzyk; H Lehvaslaiho; P Lijnzaad; C Melsopp; E Mongin; R Pettett; M Pocock; S Potter; A Rust; E Schmidt; S Searle; G Slater; J Smith; W Spooner; A Stabenau; J Stalker; E Stupka; A Ureta-Vidal; I Vastrik; M Clamp
Journal: Nucleic Acids Res Date: 2002-01-01 Impact factor: 16.971

5. Extending traditional query-based integration approaches for functional characterization of post-genomic data.

Authors: B A Eckman; A S Kosky; L A Laroco
Journal: Bioinformatics Date: 2001-07 Impact factor: 6.937

6. euGenes: a eukaryote genome information system.

Authors: Donald G Gilbert
Journal: Nucleic Acids Res Date: 2002-01-01 Impact factor: 16.971

7. Database resources of the National Center for Biotechnology Information: 2002 update.

Authors: David L Wheeler; Deanna M Church; Alex E Lash; Detlef D Leipe; Thomas L Madden; Joan U Pontius; Gregory D Schuler; Lynn M Schriml; Tatiana A Tatusova; Lukas Wagner; Barbara A Rapp
Journal: Nucleic Acids Res Date: 2002-01-01 Impact factor: 16.971

8. Large multi-chromosomal duplications encompass many members of the olfactory receptor gene family in the human genome.

Authors: B J Trask; H Massa; V Brand-Arpon; K Chan; C Friedman; O T Nguyen; E Eichler; G van den Engh; S Rouquier; H Shizuya; D Giorgi
Journal: Hum Mol Genet Date: 1998-12 Impact factor: 6.150

9. The olfactory receptor gene superfamily: data mining, classification, and nomenclature.

Authors: G Glusman; A Bahar; D Sharon; Y Pilpel; J White; D Lancet
Journal: Mamm Genome Date: 2000-11 Impact factor: 2.957

10. The complete human olfactory subgenome.

Authors: G Glusman; I Yanai; I Rubin; D Lancet
Journal: Genome Res Date: 2001-05 Impact factor: 9.043

85 in total

1. Prediction of the odorant binding site of olfactory receptor proteins by human-mouse comparisons.

Authors: Orna Man; Yoav Gilad; Doron Lancet
Journal: Protein Sci Date: 2004-01 Impact factor: 6.725

2. LIFEdb: a database for functional genomics experiments integrating information from external sources, and serving as a sample tracking system.

Authors: Detlev Bannasch; Alexander Mehrle; Karl-Heinz Glatting; Rainer Pepperkok; Annemarie Poustka; Stefan Wiemann
Journal: Nucleic Acids Res Date: 2004-01-01 Impact factor: 16.971

3. Genetic variation in the odorant receptor OR2J3 is associated with the ability to detect the "grassy" smelling odor, cis-3-hexen-1-ol.

Authors: Jeremy F McRae; Joel D Mainland; Sara R Jaeger; Kaylin A Adipietro; Hiroaki Matsunami; Richard D Newcomb
Journal: Chem Senses Date: 2012-06-19 Impact factor: 3.160

4. Uncovering the human methyltransferasome.

Authors: Tanya C Petrossian; Steven G Clarke
Journal: Mol Cell Proteomics Date: 2010-10-07 Impact factor: 5.911

5. ConceptGen: a gene set enrichment and gene set relation mapping tool.

Authors: Maureen A Sartor; Vasudeva Mahavisno; Venkateshwar G Keshamouni; James Cavalcoli; Zachary Wright; Alla Karnovsky; Rork Kuick; H V Jagadish; Barbara Mirel; Terry Weymouth; Brian Athey; Gilbert S Omenn
Journal: Bioinformatics Date: 2009-12-09 Impact factor: 6.937