PURPOSE: To evaluate the reliability and validity of a portable instrument for measuring macular pigment optical density. METHODS: The instrument is small, uses light emitting diodes as light sources and the principles of heterochromatic flicker photometry of comparing foveal and extra-foveal minimum flicker matches. It uses central fixation for the extra-foveal matches, which subjects found easier than eccentric fixation. Subjects with healthy eyes used the instrument to measure their pigment density in a number of eye clinics. RESULTS: The mean pigment density in 124 eyes in 124 individuals was 0.41 +/- 0.16 (mean +/- SD), there was no significant change with age but the density was less in females, those with light irides, smokers, subjects on diets low in precursor carotenoids and in those exposed to several hours of daylight every day or who used sun beds. CONCLUSIONS: The portable instrument gave valid and reliable data that confirmed published values for macular pigment. It was convenient to use in the clinic and has potential as a screening tool.
PURPOSE: To evaluate the reliability and validity of a portable instrument for measuring macular pigment optical density. METHODS: The instrument is small, uses light emitting diodes as light sources and the principles of heterochromatic flicker photometry of comparing foveal and extra-foveal minimum flicker matches. It uses central fixation for the extra-foveal matches, which subjects found easier than eccentric fixation. Subjects with healthy eyes used the instrument to measure their pigment density in a number of eye clinics. RESULTS: The mean pigment density in 124 eyes in 124 individuals was 0.41 +/- 0.16 (mean +/- SD), there was no significant change with age but the density was less in females, those with light irides, smokers, subjects on diets low in precursor carotenoids and in those exposed to several hours of daylight every day or who used sun beds. CONCLUSIONS: The portable instrument gave valid and reliable data that confirmed published values for macular pigment. It was convenient to use in the clinic and has potential as a screening tool.
Authors: R de Kinkelder; R L P van der Veen; F D Verbaak; D J Faber; T G van Leeuwen; T T J M Berendschot Journal: Eye (Lond) Date: 2010-11-05 Impact factor: 3.775
Authors: Alessandro Iannaccone; Marco Mura; Kevin T Gallaher; Elizabeth J Johnson; William Andrew Todd; Emily Kenyon; Tarsha L Harris; Tamara Harris; Suzanne Satterfield; Karen C Johnson; Stephen B Kritchevsky Journal: Invest Ophthalmol Vis Sci Date: 2007-04 Impact factor: 4.799
Authors: Robin G Abell; Alex W Hewitt; Marko Andric; Penelope L Allen; Nitin Verma Journal: Graefes Arch Clin Exp Ophthalmol Date: 2014-01-05 Impact factor: 3.117
Authors: Laura Patryas; Neil R A Parry; Dave Carden; Tariq Aslam; Ian J Murray Journal: Graefes Arch Clin Exp Ophthalmol Date: 2014-01-12 Impact factor: 3.117