Literature DB >> 12512625

Characterization of the DGAT1 gene in the New Zealand dairy population.

R J Spelman1, C A Ford, P McElhinney, G C Gregory, R G Snell.   

Abstract

Recently, DGAT1 was identified as the gene that underlies the QTL for bovine milk production on chromosome 14. This study investigated the effect of the reported polymorphism in three dairy breeds in New Zealand. Statistically significant results were identified for milk fat, milk protein, and volume for Jersey and Holstein-Friesian breeds, and only milk volume for Ayrshires. The average allele substitution effects were 2 to 3 kg of protein and 120 to 130 l milk for both the Jersey and Holstein-Friesian breeds. For milk fat, the average allele substitution effect was 6 kg for Holstein-Friesians and 3 kg for Jerseys. In all breeds, where the polymorphism increased milk fat yield, it decreased milk protein yield and milk volume.

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Year:  2002        PMID: 12512625     DOI: 10.3168/jds.S0022-0302(02)74440-8

Source DB:  PubMed          Journal:  J Dairy Sci        ISSN: 0022-0302            Impact factor:   4.034


  31 in total

1.  Genetic and functional confirmation of the causality of the DGAT1 K232A quantitative trait nucleotide in affecting milk yield and composition.

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Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-24       Impact factor: 11.205

2.  An Equation to Predict the Accuracy of Genomic Values by Combining Data from Multiple Traits, Populations, or Environments.

Authors:  Yvonne C J Wientjes; Piter Bijma; Roel F Veerkamp; Mario P L Calus
Journal:  Genetics       Date:  2015-12-04       Impact factor: 4.562

Review 3.  Mapping genes for complex traits in domestic animals and their use in breeding programmes.

Authors:  Michael E Goddard; Ben J Hayes
Journal:  Nat Rev Genet       Date:  2009-06       Impact factor: 53.242

Review 4.  A critical analysis of production-associated DNA polymorphisms in the genes of cattle, goat, sheep, and pig.

Authors:  Eveline M Ibeagha-Awemu; Patrick Kgwatalala; Xin Zhao
Journal:  Mamm Genome       Date:  2008-10-04       Impact factor: 2.957

5.  Effects of acyl-CoA:diacylglycerol acyl transferase 1 (DGAT1) gene on milk production traits in crossbred Holstein dairy cattle.

Authors:  Amonrat Molee; Natthaya Duanghaklang; Pongchan Na-Lampang
Journal:  Trop Anim Health Prod       Date:  2011-09-01       Impact factor: 1.559

Review 6.  Mammalian triacylglycerol metabolism: synthesis, lipolysis, and signaling.

Authors:  Rosalind A Coleman; Douglas G Mashek
Journal:  Chem Rev       Date:  2011-06-01       Impact factor: 60.622

7.  The effect of linkage disequilibrium and family relationships on the reliability of genomic prediction.

Authors:  Yvonne C J Wientjes; Roel F Veerkamp; Mario P L Calus
Journal:  Genetics       Date:  2012-12-24       Impact factor: 4.562

8.  Genetic association between SNPs in the DGAT1 gene and milk production traits in Murrah buffaloes.

Authors:  Ana Cláudia de Freitas; Gregório Miguel Ferreira de Camargo; Nedenia Bonvino Stafuzza; Rusbel Raul Aspilcueta-Borquis; Guilherme Costa Venturini; Marina Mortati Dias; Diercles Francisco Cardoso; Humberto Tonhati
Journal:  Trop Anim Health Prod       Date:  2016-07-28       Impact factor: 1.559

9.  Novel use of derived genotype probabilities to discover significant dominance effects for milk production traits in dairy cattle.

Authors:  Teide-Jens Boysen; Claas Heuer; Jens Tetens; Fritz Reinhardt; Georg Thaller
Journal:  Genetics       Date:  2012-12-05       Impact factor: 4.562

10.  Accuracy of genomic breeding values in multi-breed dairy cattle populations.

Authors:  Ben J Hayes; Phillip J Bowman; Amanda C Chamberlain; Klara Verbyla; Mike E Goddard
Journal:  Genet Sel Evol       Date:  2009-11-24       Impact factor: 4.297

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