Literature DB >> 12489015

Nitric oxide inhibits cysteine proteinases and alcohol dehydrogenase 2 of Entamoeba histolytica.

Rama Siman-Tov1, Serge Ankri.   

Abstract

Nitric oxide is involved in the neutrophil and macrophage killing of the protozoan parasite Entamoeba histolytica. In the present study, we found that cysteine proteinases, significant contributors to amebic virulence and alcohol dehydrogenase 2, an enzyme absolutely required for the survival of the parasite, are both significantly inhibited by S-nitroso-glutathione, a physiological nitric oxide donor, within the concentration range 0.5-2.0 m M.

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Year:  2002        PMID： 12489015     DOI： 10.1007/s00436-002-0716-2

Source DB:  PubMed          Journal:  Parasitol Res        ISSN： 0932-0113            Impact factor:   2.289


  15 in total

1.  Intracellular release of nitric oxide by NCX 972, an NO-releasing metronidazole, enhances in vitro killing of Entamoeba histolytica.

Authors:  Anna Sannella; Luigi Gradoni; Tiziana Persichini; Ennio Ongini; Giorgio Venturini; Marco Colasanti
Journal:  Antimicrob Agents Chemother       Date:  2003-07       Impact factor: 5.191

2.  Expression of inducible nitric oxide synthase mRNA and nitric oxide production during the development of liver abscess in hamster inoculated with Entamoeba histolytica.

Authors:  Joel Ramírez-Emiliano; Angélica González-Hernández; Sergio Arias-Negrete
Journal:  Curr Microbiol       Date:  2005-06-13       Impact factor: 2.188

Review 3.  Crosstalk at the initial encounter: interplay between host defense and ameba survival strategies.

Authors:  Xiaoti Guo; Eric Houpt; William A Petri
Journal:  Curr Opin Immunol       Date:  2007-08-16       Impact factor: 7.486

4.  S-Nitrosated Polypropylene Sulfide Nanoparticles for Thiol-Dependent Transnitrosation and Toxicity Against Adult Female Filarial Worms.

Authors:  Alex Schudel; Timothy Kassis; J Brandon Dixon; Susan N Thomas
Journal:  Adv Healthc Mater       Date:  2015-05-04       Impact factor: 9.933

5.  The Entamoeba histolytica Dnmt2 homolog (Ehmeth) confers resistance to nitrosative stress.

Authors:  Rivi Hertz; Ayala Tovy; Michael Kirschenbaum; Meirav Geffen; Tomoyoshi Nozaki; Noam Adir; Serge Ankri
Journal:  Eukaryot Cell       Date:  2014-02-21

Review 6.  Immune responses against protozoan parasites: a focus on the emerging role of Nod-like receptors.

Authors:  Prajwal Gurung; Thirumala-Devi Kanneganti
Journal:  Cell Mol Life Sci       Date:  2016-03-31       Impact factor: 9.261

Review 7.  The dynamic interdependence of amebiasis, innate immunity, and undernutrition.

Authors:  Hans P Verkerke; William A Petri; Chelsea S Marie
Journal:  Semin Immunopathol       Date:  2012-11-01       Impact factor: 9.623

8.  Glucose starvation boosts Entamoeba histolytica virulence.

Authors:  Ayala Tovy; Rivka Hertz; Rama Siman-Tov; Sylvie Syan; Daniela Faust; Nancy Guillen; Serge Ankri
Journal:  PLoS Negl Trop Dis       Date:  2011-08-02

9.  Proteomic identification of S-nitrosylated proteins in the parasite Entamoeba histolytica by resin-assisted capture: insights into the regulation of the Gal/GalNAc lectin by nitric oxide.

Authors:  Rivka Hertz; Shani Ben Lulu; Preeti Shahi; Meirav Trebicz-Geffen; Moran Benhar; Serge Ankri
Journal:  PLoS One       Date:  2014-03-13       Impact factor: 3.240

Review 10.  Peroxynitrite and peroxiredoxin in the pathogenesis of experimental amebic liver abscess.

Authors:  Judith Pacheco-Yepez; Rosa Adriana Jarillo-Luna; Manuel Gutierrez-Meza; Edgar Abarca-Rojano; Bruce Allan Larsen; Rafael Campos-Rodriguez
Journal:  Biomed Res Int       Date:  2014-04-15       Impact factor: 3.411
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