Literature DB >> 12485352

Free drug fraction vs free drug concentration: a matter of frequent confusion.

P L Toutain1, A Bousquet-Melou.   

Abstract

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Year:  2002        PMID: 12485352     DOI: 10.1046/j.1365-2885.2002.00442.x

Source DB:  PubMed          Journal:  J Vet Pharmacol Ther        ISSN: 0140-7783            Impact factor:   1.786


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  25 in total

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3.  Nonlinear protein binding of phenytoin in clinical practice: Development and validation of a mechanistic prediction model.

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4.  Interethnic scaling of fraction unbound of a drug in plasma and volume of distribution: an analysis of extrapolation from Caucasians to Chinese.

Authors:  Guo Yu; Hong-Hao Zhou; Qing-Shan Zheng; Guo-Fu Li
Journal:  Eur J Clin Pharmacol       Date:  2018-12-19       Impact factor: 2.953

Review 5.  Importance of relating efficacy measures to unbound drug concentrations for anti-infective agents.

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6.  Free dug concentrations in pregnancy: Bound to measure unbound?

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7.  Assessing Toxicokinetic Uncertainty and Variability in Risk Prioritization.

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8.  Use of microdose phenotyping to individualise dosing of patients.

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9.  The clinical relevance of plasma protein binding changes.

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Review 10.  Pharmacokinetic drug interactions in liver disease: An update.

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