| Literature DB >> 12465946 |
Xu Wu1, Sheng Ding, Qiang Ding, Nathanael S Gray, Peter G Schultz.
Abstract
Purmorphamine, which is a 2,6,9-trisubstituted purine compound, was discovered through cell-based high-throughput screening from a heterocycle combinatorial library. It differentiates multipotent mesenchymal progenitor cells into an osteoblast lineage. It will serve as a unique chemical tool to study the molecular mechanisms of osteogenesis of stem cells and bone development.Entities:
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Year: 2002 PMID： 12465946 DOI： 10.1021/ja0283908
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419