Literature DB >> 12458076

Developments in RNA chemistry, a personal view.

F Eckstein1.   

Abstract

This review describes some of the contributions of chemistry to the RNA field with a personal bias towards the phosphorothioate modification and the derivatives at the ribose 2'-position. The usefulness of these modifications is discussed and documented with some examples.

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Year:  2002        PMID： 12458076     DOI： 10.1016/s0300-9084(02)01459-1

Source DB:  PubMed          Journal:  Biochimie        ISSN： 0300-9084            Impact factor:   4.079


  13 in total

1.  Selection and evolution of NTP-specific aptamers.

Authors:  Laure Weill; Dominique Louis; Bruno Sargueil
Journal:  Nucleic Acids Res       Date:  2004-09-27       Impact factor: 16.971

Review 2.  Silencing disease genes in the laboratory and the clinic.

Authors:  Jonathan K Watts; David R Corey
Journal:  J Pathol       Date:  2011-11-09       Impact factor: 7.996

3.  The role of phosphate groups in the VS ribozyme-substrate interaction.

Authors:  Yana S Kovacheva; Svetomir B Tzokov; Iain A Murray; Jane A Grasby
Journal:  Nucleic Acids Res       Date:  2004-12-01       Impact factor: 16.971

Review 4.  Chemical modification: the key to clinical application of RNA interference?

Authors:  David R Corey
Journal:  J Clin Invest       Date:  2007-12       Impact factor: 14.808

5.  Synthesis of Boranoate, Selenoate, and Thioate Analogs of AZTp(4)A and Ap(4)A.

Authors:  Qianwei Han; Stefan G Sarafianos; Eddy Arnold; Michael A Parniak; Barbara L Gaffney; Roger A Jones
Journal:  Tetrahedron       Date:  2009-09-19       Impact factor: 2.457

6.  Therapeutic Potential of OMe-PS-miR-29b1 for Treating Liver Fibrosis.

Authors:  Virender Kumar; Vinod Kumar; Jiangtao Luo; Ram I Mahato
Journal:  Mol Ther       Date:  2018-09-01       Impact factor: 11.454

7.  RNA interference using boranophosphate siRNAs: structure-activity relationships.

Authors:  Allison H S Hall; Jing Wan; Erin E Shaughnessy; Barbara Ramsay Shaw; Kenneth A Alexander
Journal:  Nucleic Acids Res       Date:  2004-11-15       Impact factor: 16.971

8.  Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering.

Authors:  Jesper B Bramsen; Jørgen Kjems
Journal:  Front Genet       Date:  2012-08-20       Impact factor: 4.599

Review 9.  Splicing therapy for neuromuscular disease.

Authors:  Andrew G L Douglas; Matthew J A Wood
Journal:  Mol Cell Neurosci       Date:  2013-04-28       Impact factor: 4.314

10.  Short-interference RNAs: becoming medicines.

Authors:  Tamara Martínez; Ana Isabel Jiménez; Covadonga Pañeda
Journal:  EXCLI J       Date:  2015-06-15       Impact factor: 4.068
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