Literature DB >> 12455968

Gcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress.

Alan G Hinnebusch1, Krishnamurthy Natarajan.   

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Year:  2002        PMID: 12455968      PMCID: PMC118051          DOI: 10.1128/EC.01.1.22-32.2002

Source DB:  PubMed          Journal:  Eukaryot Cell        ISSN: 1535-9786


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  91 in total

1.  The proteasome regulates the UV-induced activation of the AP-1-like transcription factor Gcn4.

Authors:  M L Stitzel; R Durso; J C Reese
Journal:  Genes Dev       Date:  2001-01-15       Impact factor: 11.361

2.  The tRNA-binding moiety in GCN2 contains a dimerization domain that interacts with the kinase domain and is required for tRNA binding and kinase activation.

Authors:  H Qiu; J Dong; C Hu; C S Francklyn; A G Hinnebusch
Journal:  EMBO J       Date:  2001-03-15       Impact factor: 11.598

3.  Promoter-specific binding of Rap1 revealed by genome-wide maps of protein-DNA association.

Authors:  J D Lieb; X Liu; D Botstein; P O Brown
Journal:  Nat Genet       Date:  2001-08       Impact factor: 38.330

4.  Budding yeast GCN1 binds the GI domain to activate the eIF2alpha kinase GCN2.

Authors:  H Kubota; K Ota; Y Sakaki; T Ito
Journal:  J Biol Chem       Date:  2001-02-28       Impact factor: 5.157

5.  Repression of GCN4 mRNA translation by nitrogen starvation in Saccharomyces cerevisiae.

Authors:  O Grundmann; H U Mösch; G H Braus
Journal:  J Biol Chem       Date:  2001-05-16       Impact factor: 5.157

6.  Gcn2 mediates Gcn4 activation in response to glucose stimulation or UV radiation not via GCN4 translation.

Authors:  I Marbach; R Licht; H Frohnmeyer; D Engelberg
Journal:  J Biol Chem       Date:  2001-02-28       Impact factor: 5.157

7.  TOR modulates GCN4-dependent expression of genes turned on by nitrogen limitation.

Authors:  L Valenzuela; C Aranda; A González
Journal:  J Bacteriol       Date:  2001-04       Impact factor: 3.490

8.  Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeast.

Authors:  K Natarajan; M R Meyer; B M Jackson; D Slade; C Roberts; A G Hinnebusch; M J Marton
Journal:  Mol Cell Biol       Date:  2001-07       Impact factor: 4.272

9.  Negative regulation of Gcn4 and Msn2 transcription factors by Srb10 cyclin-dependent kinase.

Authors:  Y Chi; M J Huddleston; X Zhang; R A Young; R S Annan; S A Carr; R J Deshaies
Journal:  Genes Dev       Date:  2001-05-01       Impact factor: 11.361

10.  Remodeling of yeast genome expression in response to environmental changes.

Authors:  H C Causton; B Ren; S S Koh; C T Harbison; E Kanin; E G Jennings; T I Lee; H L True; E S Lander; R A Young
Journal:  Mol Biol Cell       Date:  2001-02       Impact factor: 4.138

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  144 in total

1.  Solution structure of the RWD domain of the mouse GCN2 protein.

Authors:  Nobukazu Nameki; Misao Yoneyama; Seizo Koshiba; Naoya Tochio; Makoto Inoue; Eiko Seki; Takayoshi Matsuda; Yasuko Tomo; Takushi Harada; Kohei Saito; Naohiro Kobayashi; Takashi Yabuki; Masaaki Aoki; Emi Nunokawa; Natsuko Matsuda; Noriko Sakagami; Takaho Terada; Mikako Shirouzu; Mayumi Yoshida; Hiroshi Hirota; Takashi Osanai; Akiko Tanaka; Takahiro Arakawa; Piero Carninci; Jun Kawai; Yoshihide Hayashizaki; Kengo Kinoshita; Peter Güntert; Takanori Kigawa; Shigeyuki Yokoyama
Journal:  Protein Sci       Date:  2004-08       Impact factor: 6.725

2.  Loss of translational control in yeast compromised for the major mRNA decay pathway.

Authors:  L E A Holmes; S G Campbell; S K De Long; A B Sachs; M P Ashe
Journal:  Mol Cell Biol       Date:  2004-04       Impact factor: 4.272

3.  Parasite-specific eIF2 (eukaryotic initiation factor-2) kinase required for stress-induced translation control.

Authors:  William J Sullivan; Jana Narasimhan; Micah M Bhatti; Ronald C Wek
Journal:  Biochem J       Date:  2004-06-01       Impact factor: 3.857

4.  Maf1 protein, repressor of RNA polymerase III, indirectly affects tRNA processing.

Authors:  Iwona Karkusiewicz; Tomasz W Turowski; Damian Graczyk; Joanna Towpik; Nripesh Dhungel; Anita K Hopper; Magdalena Boguta
Journal:  J Biol Chem       Date:  2011-09-22       Impact factor: 5.157

5.  Gcn4p-mediated transcriptional repression of ribosomal protein genes under amino-acid starvation.

Authors:  Yoo Jin Joo; Jin-Ha Kim; Un-Beom Kang; Myeong-Hee Yu; Joon Kim
Journal:  EMBO J       Date:  2010-12-24       Impact factor: 11.598

Review 6.  Metabolic remodeling in iron-deficient fungi.

Authors:  Caroline C Philpott; Sébastien Leidgens; Avery G Frey
Journal:  Biochim Biophys Acta       Date:  2012-01-27

7.  Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development.

Authors:  Yann-Gaël Gangloff; Matthias Mueller; Stephen G Dann; Petr Svoboda; Melanie Sticker; Jean-Francois Spetz; Sung Hee Um; Eric J Brown; Silvia Cereghini; George Thomas; Sara C Kozma
Journal:  Mol Cell Biol       Date:  2004-11       Impact factor: 4.272

8.  Amino acid starvation and Gcn4p regulate adhesive growth and FLO11 gene expression in Saccharomyces cerevisiae.

Authors:  Gerhard H Braus; Olav Grundmann; Stefan Brückner; Hans-Ulrich Mösch
Journal:  Mol Biol Cell       Date:  2003-06-27       Impact factor: 4.138

9.  Severe adenine starvation activates Ty1 transcription and retrotransposition in Saccharomyces cerevisiae.

Authors:  Anne-Laure Todeschini; Antonin Morillon; Mathias Springer; Pascale Lesage
Journal:  Mol Cell Biol       Date:  2005-09       Impact factor: 4.272

10.  The TAF9 C-terminal conserved region domain is required for SAGA and TFIID promoter occupancy to promote transcriptional activation.

Authors:  Malika Saint; Sonal Sawhney; Ishani Sinha; Rana Pratap Singh; Rashmi Dahiya; Anushikha Thakur; Rahul Siddharthan; Krishnamurthy Natarajan
Journal:  Mol Cell Biol       Date:  2014-02-18       Impact factor: 4.272

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