Literature DB >> 12431387

Interleukin-15 and the regulation of lymphoid homeostasis.

James Lodolce1, Patrick Burkett, Rima Koka, David Boone, Marcia Chien, Faye Chan, Michelle Madonia, Sophia Chai, Averil Ma.   

Abstract

Interleukin-15 (IL-15) is a cytokine that plays unique roles in both innate and adaptive immune cell homeostasis. While early studies suggested that IL-15 resembled IL-2, more recent work suggests that IL-15 may play multiple unique roles in immune homeostasis befitting its pleiotropic expression pattern. This review will focus on recent studies that highlight some of these functions.

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Year:  2002        PMID: 12431387     DOI: 10.1016/s0161-5890(02)00211-0

Source DB:  PubMed          Journal:  Mol Immunol        ISSN: 0161-5890            Impact factor:   4.407


  27 in total

1.  IL-15 Superagonist-Mediated Immunotoxicity: Role of NK Cells and IFN-γ.

Authors:  Yin Guo; Liming Luan; Whitney Rabacal; Julia K Bohannon; Benjamin A Fensterheim; Antonio Hernandez; Edward R Sherwood
Journal:  J Immunol       Date:  2015-07-27       Impact factor: 5.422

2.  Survival adjustment of mature dendritic cells by IL-15.

Authors:  Sigrid P Dubois; Thomas A Waldmann; Jürgen R Müller
Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-02       Impact factor: 11.205

3.  The role of IL-15 in activating STAT5 and fine-tuning IL-17A production in CD4 T lymphocytes.

Authors:  Pushpa Pandiyan; Xiang-Ping Yang; Senthil S Saravanamuthu; Lixin Zheng; Satoru Ishihara; John J O'Shea; Michael J Lenardo
Journal:  J Immunol       Date:  2012-09-19       Impact factor: 5.422

4.  Molecular classification and subtype-specific characterization of skin cutaneous melanoma by aggregating multiple genomic platform data.

Authors:  Xiaofan Lu; Qianyuan Zhang; Yue Wang; Liya Zhang; Huiling Zhao; Chen Chen; Yaoyan Wang; Shengjie Liu; Tao Lu; Fei Wang; Fangrong Yan
Journal:  J Cancer Res Clin Oncol       Date:  2018-06-11       Impact factor: 4.553

5.  IL-15-deficient mice develop enhanced allergic responses to airway allergen exposure.

Authors:  C B Mathias; C M Schramm; L A Guernsey; C A Wu; S H Polukort; J Rovatti; J Ser-Dolansky; E Secor; S S Schneider; R S Thrall; H L Aguila
Journal:  Clin Exp Allergy       Date:  2017-02-07       Impact factor: 5.018

6.  Repression of interferon regulatory factor 1 by hepatitis C virus core protein results in inhibition of antiviral and immunomodulatory genes.

Authors:  Anna R Ciccaglione; Emilia Stellacci; Cinzia Marcantonio; Valentina Muto; Michele Equestre; Giulia Marsili; Maria Rapicetta; Angela Battistini
Journal:  J Virol       Date:  2006-10-18       Impact factor: 5.103

7.  Modulation of interleukin-15-induced suppression of human neutrophil apoptosis by TNFalpha.

Authors:  Xiuping Liu; Changyun Xiong; Chunhong Li; Deguang Yang
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2007-08

8.  ALT-803 Transiently Reduces Simian Immunodeficiency Virus Replication in the Absence of Antiretroviral Treatment.

Authors:  Amy L Ellis-Connell; Alexis J Balgeman; Katie R Zarbock; Gabrielle Barry; Andrea Weiler; Jack O Egan; Emily K Jeng; Thomas Friedrich; Jeffrey S Miller; Ashley T Haase; Timothy W Schacker; Hing C Wong; Eva Rakasz; Shelby L O'Connor
Journal:  J Virol       Date:  2018-01-17       Impact factor: 5.103

9.  IL-15 produced and trans-presented by DCs underlies homeostatic competition between CD8 and {gamma}{delta} T cells in vivo.

Authors:  Jeong-su Do; Booki Min
Journal:  Blood       Date:  2009-04-20       Impact factor: 22.113

Review 10.  The biological and clinical importance of the 'new generation' cytokines in rheumatic diseases.

Authors:  Cem Gabay; Iain B McInnes
Journal:  Arthritis Res Ther       Date:  2009-05-19       Impact factor: 5.156

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