Literature DB >> 12415319

Conrad Hal Waddington: the last Renaissance biologist?

Jonathan M W Slack1.   

Abstract

Conrad Hal Waddington was a leading embryologist and geneticist from the 1930s to the 1950s. He is remembered mainly for his concepts of the 'epigenetic landscape' and 'genetic assimilation'. This article reviews his life and work, and enquires to what extent his ideas are relevant tools for understanding the biological problems of today.

Entities:  

Mesh：

Year:  2002        PMID： 12415319     DOI： 10.1038/nrg933

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN： 1471-0056            Impact factor:   53.242


  62 in total

Review 1.  Epigenetic memories: structural marks or active circuits?

Authors:  Floriane Nicol-Benoît; Pascale Le-Goff; Yves Le-Dréan; Florence Demay; Farzad Pakdel; Gilles Flouriot; Denis Michel
Journal:  Cell Mol Life Sci       Date:  2012-02-14       Impact factor: 9.261

2.  Some applications of pharmacogenomics and epigenetics in drug development and use in pursuit of personalized medicine.

Authors:  M C Powanda; E D Moyer
Journal:  Inflammopharmacology       Date:  2012-07-07       Impact factor: 4.473

Review 3.  Regeneration: The origin of cancer or a possible cure?

Authors:  Néstor J Oviedo; Wendy S Beane
Journal:  Semin Cell Dev Biol       Date:  2009-04-14       Impact factor: 7.727

4.  Shaping embryos in Barcelona.

Authors:  Michel Labouesse; Lilianna Solnica-Krezel
Journal:  Nat Cell Biol       Date:  2009-01       Impact factor: 28.824

Review 5.  Non-genetic heterogeneity of cells in development: more than just noise.

Authors:  Sui Huang
Journal:  Development       Date:  2009-12       Impact factor: 6.868

Review 6.  Systems biology of stem cells: three useful perspectives to help overcome the paradigm of linear pathways.

Authors:  Sui Huang
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2011-08-12       Impact factor: 6.237

7.  Microfluidic hydrodynamic cellular patterning for systematic formation of co-culture spheroids.

Authors:  Yu-suke Torisawa; Bobak Mosadegh; Gary D Luker; Maria Morell; K Sue O'Shea; Shuichi Takayama
Journal:  Integr Biol (Camb)       Date:  2009-10-22       Impact factor: 2.192

Review 8.  Programmed and self-organized flow of information during morphogenesis.

Authors:  Claudio Collinet; Thomas Lecuit
Journal:  Nat Rev Mol Cell Biol       Date:  2021-01-22       Impact factor: 94.444

9.  Global view of bionetwork dynamics: adaptive landscape.

Authors:  Ping Ao
Journal:  J Genet Genomics       Date:  2009-02       Impact factor: 4.275

10.  Cause and consequences of genetic and epigenetic alterations in human cancer.

Authors:  B Sadikovic; K Al-Romaih; J A Squire; M Zielenska
Journal:  Curr Genomics       Date:  2008-09       Impact factor: 2.236
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.