Literature DB >> 12410036

Treatment of recurrent corneal erosions using autologous serum.

Jose Manuel Benítez del Castillo1, Jose Maria Martínez de la Casa, Ricardo Cuiña Sardiña, Rosalia Méndez Fernández, Julian García Feijoo, Alfredo Castillo Gómez, Maria Matilla Rodero, Julian García Sánchez.   

Abstract

PURPOSE: To study the effect of autologous serum in the treatment of recurrent corneal erosions.
METHODS: Eleven eyes of 11 consecutive patients with acute macroform corneal erosions who had suffered several relapses despite receiving different types of treatment were analyzed from November 2000 to February 2002. All patients were treated with autologous serum for 3 months.
RESULTS: Mean follow-up time was 9.4 +/- 3.7 months (range, 4-16). No side effects were noted in any of the treated patients. Treatments prior to the use of autologous serum had failed to avoid recurrences in all the patients, with the mean recurrence rate being 2.2 recurrences per month of follow-up. After the onset of serum treatment, only a single recurrence was recorded in three of the patients (0.028 recurrences per month of follow-up).
CONCLUSION: The use of autologous serum for the treatment of patients with recurrent corneal erosion is effective and safe in reducing the number of recurrences experienced by patients.

Entities:  

Mesh:

Year:  2002        PMID: 12410036     DOI: 10.1097/00003226-200211000-00010

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  23 in total

1.  An optimised protocol for the production of autologous serum eyedrops.

Authors:  L Liu; D Hartwig; S Harloff; P Herminghaus; T Wedel; G Geerling
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Review 2.  [Albumin eye drops for treatment of ocular surface diseases].

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4.  The efficacy of autologous serum eye drops for severe dry eye syndrome: a randomized double-blind crossover study.

Authors:  Ali Riza Cenk Celebi; Cemalettin Ulusoy; G Ertugrul Mirza
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-02-25       Impact factor: 3.117

5.  Fingerprick autologous blood: a novel treatment for dry eye syndrome.

Authors:  J Than; S Balal; J Wawrzynski; N Nesaratnam; G M Saleh; J Moore; A Patel; S Shah; B Sharma; B Kumar; J Smith; A Sharma
Journal:  Eye (Lond)       Date:  2017-06-16       Impact factor: 3.775

6.  Umbilical cord blood serum therapy for the management of persistent corneal epithelial defects.

Authors:  Elif Erdem; Meltem Yagmur; Inan Harbiyeli; Hande Taylan-Sekeroglu; Reha Ersoz
Journal:  Int J Ophthalmol       Date:  2014-10-18       Impact factor: 1.779

7.  Effect of autologous platelet-rich plasma on persistent corneal epithelial defect after infectious keratitis.

Authors:  Kyoung Min Kim; Yong-Tae Shin; Hong Kyun Kim
Journal:  Jpn J Ophthalmol       Date:  2012-09-13       Impact factor: 2.447

8.  Cultivated autologous limbal epithelial transplantation for symptomatic bullous keratopathy.

Authors:  Yoshiyuki Satake; Shigeto Shimmura; Jun Shimazaki
Journal:  BMJ Case Rep       Date:  2009-04-14

Review 9.  Autologous serum eye drops for ocular surface disorders.

Authors:  G Geerling; S Maclennan; D Hartwig
Journal:  Br J Ophthalmol       Date:  2004-11       Impact factor: 4.638

10.  Recurrence rate and subjective symptoms after standardized (Hamburg protocol) phototherapeutic keratectomy on recurrent corneal erosions.

Authors:  J Mehlan; J Steinberg; L Traber; T Katz; S J Linke
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2016-08-22       Impact factor: 3.117

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