Literature DB >> 21686396

Cultivated autologous limbal epithelial transplantation for symptomatic bullous keratopathy.

Yoshiyuki Satake1, Shigeto Shimmura, Jun Shimazaki.   

Abstract

We report the clinical outcome of cultivated autologous limbal epithelial transplantation for symptomatic bullous keratopathy in an 87-year-old female patient presenting with recurrent corneal erosion and intractable ocular pain. The patient refused corneal transplantation, and transplantation of a cultivated autologous limbal epithelial sheet was carried out to free her of the symptoms associated with chronic pseudophakic bullous keratopathy. Both integrity of transplanted epithelium and relief from intolerable ocular pain were achieved and maintained immediately after surgery. No complications were noted in either the transplanted eye or donor eye during the 43-month follow-up period. Our findings support that patients with bullous keratopathy not consenting to procedures to improve visual acuity in whom the primary aim is relief of symptoms may benefit from cultivated autologous limbal epithelial transplantation.

Entities:  

Year:  2009        PMID: 21686396      PMCID: PMC3029893          DOI: 10.1136/bcr.11.2008.1239

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  11 in total

1.  Amniotic membrane transplantation for symptomatic bullous keratopathy.

Authors:  R T Pires; S C Tseng; P Prabhasawat; V Puangsricharern; S L Maskin; J C Kim; D T Tan
Journal:  Arch Ophthalmol       Date:  1999-10

2.  Amniotic membrane transplantation with anterior stromal micropuncture for treatment of painful bullous keratopathy in eyes with poor visual potential.

Authors:  Baris Sonmez; Brian T Kim; Anthony J Aldave
Journal:  Cornea       Date:  2007-02       Impact factor: 2.651

3.  Long-standing bullous keratopathy is associated with peripheral conjunctivalization and limbal deficiency.

Authors:  Yuichi Uchino; Eiki Goto; Yoji Takano; Murat Dogru; Naoshi Shinozaki; Shigeto Shimmura; Yukiko Yagi; Kazuo Tsubota; Jun Shimazaki
Journal:  Ophthalmology       Date:  2006-05-02       Impact factor: 12.079

4.  Anterior stromal puncture in the treatment of bullous keratopathy: six-month follow-up.

Authors:  J A Gomes; D K Haraguchi; D U Zambrano; L Izquierdo Júnior; M C Cunha; D de Freitas
Journal:  Cornea       Date:  2001-08       Impact factor: 2.651

5.  Cultivated corneal epithelial stem cell transplantation in ocular surface disorders.

Authors:  N Koizumi; T Inatomi; T Suzuki; C Sotozono; S Kinoshita
Journal:  Ophthalmology       Date:  2001-09       Impact factor: 12.079

6.  Antiinflammatory effects of amniotic membrane transplantation in ocular surface disorders.

Authors:  S Shimmura; J Shimazaki; Y Ohashi; K Tsubota
Journal:  Cornea       Date:  2001-05       Impact factor: 2.651

7.  Symptomatic management of postoperative bullous keratopathy with nonpreserved human amniotic membrane.

Authors:  Luis F Mejía; Juan P Santamaría; Claudia Acosta
Journal:  Cornea       Date:  2002-05       Impact factor: 2.651

8.  Amniotic membrane transplantation for bullous keratopathy in eyes with poor visual potential.

Authors:  Edgar M Espana; Martin Grueterich; Helga Sandoval; Abraham Solomon; Eduardo Alfonso; Carol L Karp; Francisco Fantes; Scheffer C G Tseng
Journal:  J Cataract Refract Surg       Date:  2003-02       Impact factor: 3.351

9.  Transplantation of human limbal epithelium cultivated on amniotic membrane for the treatment of severe ocular surface disorders.

Authors:  Jun Shimazaki; Masayo Aiba; Eiki Goto; Naoko Kato; Shigeto Shimmura; Kazuo Tsubota
Journal:  Ophthalmology       Date:  2002-07       Impact factor: 12.079

10.  Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium.

Authors:  G Pellegrini; C E Traverso; A T Franzi; M Zingirian; R Cancedda; M De Luca
Journal:  Lancet       Date:  1997-04-05       Impact factor: 79.321

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  3 in total

Review 1.  Safety of Cultivated Limbal Epithelial Stem Cell Transplantation for Human Corneal Regeneration.

Authors:  J Behaegel; S Ní Dhubhghaill; C Koppen; N Zakaria
Journal:  Stem Cells Int       Date:  2017-03-30       Impact factor: 5.443

Review 2.  Concise Review: Altered Versus Unaltered Amniotic Membrane as a Substrate for Limbal Epithelial Cells.

Authors:  Tor Paaske Utheim; Øygunn Aass Utheim; Panagiotis Salvanos; Catherine J Jackson; Stefan Schrader; Gerd Geerling; Amer Sehic
Journal:  Stem Cells Transl Med       Date:  2018-03-23       Impact factor: 6.940

Review 3.  Recovering vision in corneal epithelial stem cell deficient eyes.

Authors:  Kiranjit K Bains; Hideki Fukuoka; Greg M Hammond; Chie Sotozono; Andrew J Quantock
Journal:  Cont Lens Anterior Eye       Date:  2019-04-29       Impact factor: 3.077

  3 in total

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