Literature DB >> 19813016

[Albumin eye drops for treatment of ocular surface diseases].

J D Unterlauft1, M Kohlhaas, I Hofbauer, K Kasper, G Geerling.   

Abstract

For more than 10 years eye drops made from autologous serum have become an established therapy to support corneal wound healing in ocular surface diseases, such as persistent epithelial defects and dry eye. Serum eye drops can only be dispensed by institutions which have obtained a specific license from the appropriate local authorities and this applies to only a few institutes in Germany. The main protein component of serum is albumin which is commercially available as a quality controlled medical product from the pharmaceutical industry and could thus be used as an alternative to autologous serum eye drops. The wound healing effect of albumin eye drops has already been demonstrated in vitro. Here we outline the therapeutic principles and present our first clinical experiences with eye drops made from albumin in the treatment of ocular surface disorders.

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Year:  2009        PMID: 19813016     DOI: 10.1007/s00347-009-2057-3

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  32 in total

1.  Treatment of recurrent corneal erosions using autologous serum.

Authors:  Jose Manuel Benítez del Castillo; Jose Maria Martínez de la Casa; Ricardo Cuiña Sardiña; Rosalia Méndez Fernández; Julian García Feijoo; Alfredo Castillo Gómez; Maria Matilla Rodero; Julian García Sánchez
Journal:  Cornea       Date:  2002-11       Impact factor: 2.651

2.  Combination of serum eye drops with hydrogel bandage contact lenses in the treatment of persistent epithelial defects.

Authors:  Stefan Schrader; Thilo Wedel; Ralf Moll; Gerd Geerling
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2006-03-17       Impact factor: 3.117

Review 3.  [Current treatment for dry eye syndrome].

Authors:  C Cursiefen; C Jacobi; T Dietrich; F E Kruse
Journal:  Ophthalmologe       Date:  2006-01       Impact factor: 1.059

4.  Topical treatment with nerve growth factor for corneal neurotrophic ulcers.

Authors:  A Lambiase; P Rama; S Bonini; G Caprioglio; L Aloe
Journal:  N Engl J Med       Date:  1998-04-23       Impact factor: 91.245

5.  [Autologous serum-eye-drops for ocular surface disorders. A literature review and recommendations for their application].

Authors:  G Geerling; D Hartwig
Journal:  Ophthalmologe       Date:  2002-12       Impact factor: 1.059

6.  Autologous serum eyedrops for dry eyes and epithelial defects: clinical and in vitro toxicity studies.

Authors:  A C Poon; G Geerling; J K Dart; G E Fraenkel; J T Daniels
Journal:  Br J Ophthalmol       Date:  2001-10       Impact factor: 4.638

7.  Topical treatment with nerve growth factor for neurotrophic keratitis.

Authors:  S Bonini; A Lambiase; P Rama; G Caprioglio; L Aloe
Journal:  Ophthalmology       Date:  2000-07       Impact factor: 12.079

8.  Treatment of persistent corneal epithelial defect by autologous serum application.

Authors:  K Tsubota; E Goto; S Shimmura; J Shimazaki
Journal:  Ophthalmology       Date:  1999-10       Impact factor: 12.079

Review 9.  Autologous serum eye drops for ocular surface disorders.

Authors:  G Geerling; S Maclennan; D Hartwig
Journal:  Br J Ophthalmol       Date:  2004-11       Impact factor: 4.638

10.  Carboxymethyl cellulose stimulates rabbit corneal epithelial wound healing.

Authors:  Qian Garrett; Shunjiang Xu; Peter A Simmons; Joseph Vehige; Ruo Zhong Xie; Ajay Kumar; Judith L Flanagan; Zhenjun Zhao; Mark D P Willcox
Journal:  Curr Eye Res       Date:  2008-07       Impact factor: 2.424

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  5 in total

Review 1.  [Diagnosis and treatment of the watering eye].

Authors:  M Schargus; G Geerling
Journal:  HNO       Date:  2017-01       Impact factor: 1.284

2.  Human albumin eye drops as a therapeutic option for the management of keratoconjunctivitis sicca secondary to chronic graft-versus-host disease after stem-cell allografting.

Authors:  J T Seki; N Sakurai; S Moldenhauer; J Dam; E G Atenafu; P M Yip; T Mazzulli; T Henderson; J Pendergrast; C Cserti; J P Velazquez; R Simpson; G Felluga; H A Messner; J H Lipton
Journal:  Curr Oncol       Date:  2015-10       Impact factor: 3.677

3.  [Bottlenecks in the availability of ophthalmological medications : Initiative of the Working Group on Ethics in Ophthalmology of the DOG and the University Eye Clinic Bonn].

Authors:  M C Herwig-Carl; K U Loeffler; I Schulze; F G Holz; G Geerling
Journal:  Ophthalmologie       Date:  2022-07-14

Review 4.  Persistent Corneal Epithelial Defects: A Review Article.

Authors:  Uma Vaidyanathan; Grant C Hopping; Harry Y Liu; Anisha N Somani; Yasmyne C Ronquillo; Phillip C Hoopes; Majid Moshirfar
Journal:  Med Hypothesis Discov Innov Ophthalmol       Date:  2019

5.  Functional lacrimal gland regeneration by transplantation of a bioengineered organ germ.

Authors:  Masatoshi Hirayama; Miho Ogawa; Masamitsu Oshima; Yurie Sekine; Kentaro Ishida; Kentaro Yamashita; Kazutaka Ikeda; Shigeto Shimmura; Tetsuya Kawakita; Kazuo Tsubota; Takashi Tsuji
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

  5 in total

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