| Literature DB >> 12391370 |
J S Wolinsky1, G Comi, M Filippi, D Ladkani, S Kadosh, G Shifroni.
Abstract
All but 6% of the subjects with relapsing remitting MS who were randomly assigned to receive glatiramer acetate or placebo for the 9-month controlled phase of the European/Canadian MRI trial entered an open-label extension with quarterly clinical and MRI evaluations for another 9 months. There was a 54% reduction in the mean number of enhanced lesions for those converted from placebo to glatiramer acetate and an additional 24.6% reduction for those always on glatiramer acetate. Over the entire study the accumulated T2 disease burden was 34.2% less for those always on glatiramer acetate.Entities:
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Year: 2002 PMID: 12391370 DOI: 10.1212/wnl.59.8.1284
Source DB: PubMed Journal: Neurology ISSN: 0028-3878 Impact factor: 9.910