Literature DB >> 19300955

Immunomodulatory treatment strategies in multiple sclerosis.

Bernd C Kieseier1, Heinz Wiendl, Verena I Leussink, Olaf Stüve.   

Abstract

Multiple sclerosis (MS) represents the prototypic inflammatory autoimmune disorder of the central nervous system and the most common cause of neurological disability in young adults. The mainstays in the immunomodulatory therapy of MS are currently interferon beta and glatiramer acetate, both of which have proven to be clinically and paraclinically effective. Current clinical evidence indicates that treatment should be initiated as early as possible. In this review we summarize available data from clinical studies on clinical efficacy of immunomodulatory drugs for treating patients with multiple sclerosis.

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Year:  2008        PMID: 19300955     DOI: 10.1007/s00415-008-6004-z

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  54 in total

1.  Interferon beta-1b in secondary progressive MS: results from a 3-year controlled study.

Authors:  Hillel Panitch; Aaron Miller; Donald Paty; Brian Weinshenker
Journal:  Neurology       Date:  2004-11-23       Impact factor: 9.910

2.  The natural history of multiple sclerosis: a geographically based study. 2. Predictive value of the early clinical course.

Authors:  B G Weinshenker; B Bass; G P Rice; J Noseworthy; W Carriere; J Baskerville; G C Ebers
Journal:  Brain       Date:  1989-12       Impact factor: 13.501

3.  European/Canadian multicenter, double-blind, randomized, placebo-controlled study of the effects of glatiramer acetate on magnetic resonance imaging--measured disease activity and burden in patients with relapsing multiple sclerosis. European/Canadian Glatiramer Acetate Study Group.

Authors:  G Comi; M Filippi; J S Wolinsky
Journal:  Ann Neurol       Date:  2001-03       Impact factor: 10.422

Review 4.  Glatiramer acetate in multiple sclerosis: update on potential mechanisms of action.

Authors:  Cinthia Farina; Martin S Weber; Edgar Meinl; Hartmut Wekerle; Reinhard Hohlfeld
Journal:  Lancet Neurol       Date:  2005-09       Impact factor: 44.182

5.  Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis. PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group.

Authors: 
Journal:  Lancet       Date:  1998-11-07       Impact factor: 79.321

6.  Do oligoclonal bands add information to MRI in first attacks of multiple sclerosis?

Authors:  M Tintoré; A Rovira; J Río; C Tur; R Pelayo; C Nos; N Téllez; H Perkal; M Comabella; J Sastre-Garriga; X Montalban
Journal:  Neurology       Date:  2007-09-19       Impact factor: 9.910

7.  Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group (MSCRG)

Authors:  L D Jacobs; D L Cookfair; R A Rudick; R M Herndon; J R Richert; A M Salazar; J S Fischer; D E Goodkin; C V Granger; J H Simon; J J Alam; D M Bartoszak; D N Bourdette; J Braiman; C M Brownscheidle; M E Coats; S L Cohan; D S Dougherty; R P Kinkel; M K Mass; F E Munschauer; R L Priore; P M Pullicino; B J Scherokman; R H Whitham
Journal:  Ann Neurol       Date:  1996-03       Impact factor: 10.422

Review 8.  Differential mechanisms of action of interferon-beta and glatiramer aetate in MS.

Authors:  V Wee Yong
Journal:  Neurology       Date:  2002-09-24       Impact factor: 9.910

Review 9.  The contribution of magnetic resonance imaging to the diagnosis of multiple sclerosis.

Authors:  F Fazekas; F Barkhof; M Filippi; R I Grossman; D K Li; W I McDonald; H F McFarland; D W Paty; J H Simon; J S Wolinsky; D H Miller
Journal:  Neurology       Date:  1999-08-11       Impact factor: 9.910

10.  Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis.

Authors:  W I McDonald; A Compston; G Edan; D Goodkin; H P Hartung; F D Lublin; H F McFarland; D W Paty; C H Polman; S C Reingold; M Sandberg-Wollheim; W Sibley; A Thompson; S van den Noort; B Y Weinshenker; J S Wolinsky
Journal:  Ann Neurol       Date:  2001-07       Impact factor: 10.422

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  7 in total

1.  Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: a weighted genetic risk score.

Authors:  Philip L De Jager; Lori B Chibnik; Jing Cui; Joachim Reischl; Stephan Lehr; K Claire Simon; Cristin Aubin; David Bauer; Jürgen F Heubach; Rupert Sandbrink; Michaela Tyblova; Petra Lelkova; Eva Havrdova; Christoph Pohl; Dana Horakova; Alberto Ascherio; David A Hafler; Elizabeth W Karlson
Journal:  Lancet Neurol       Date:  2009-10-29       Impact factor: 44.182

2.  Exacerbation history is associated with medication and appointment adherence in MS.

Authors:  Laura M Hancock; Jared M Bruce; Sharon G Lynch
Journal:  J Behav Med       Date:  2011-01-23

3.  IFN-beta inhibits dendritic cell migration through STAT-1-mediated transcriptional suppression of CCR7 and matrix metalloproteinase 9.

Authors:  Jui-Hung Yen; Weimin Kong; Doina Ganea
Journal:  J Immunol       Date:  2010-02-26       Impact factor: 5.422

4.  Mycophenolate mofetil in combination with interferon beta-1a in the treatment of relapsing-remitting multiple sclerosis: A preliminary study.

Authors:  Masoud Etemadifar; Mojtaba Kazemi; Ahmad Chitsaz; Ali Hekmatnia; Nazila Tayari; Amirhossein Ghazavi; Amir Hadi Maghzi
Journal:  J Res Med Sci       Date:  2011-01       Impact factor: 1.852

5.  Perspectives on the use of multiple sclerosis risk genes for prediction.

Authors:  Naghmeh Jafari; Linda Broer; Cornelia M van Duijn; A Cecile J W Janssens; Rogier Q Hintzen
Journal:  PLoS One       Date:  2011-12-02       Impact factor: 3.240

6.  Immunosuppressive potential of human amnion epithelial cells in the treatment of experimental autoimmune encephalomyelitis.

Authors:  Courtney A McDonald; Natalie L Payne; Guizhi Sun; Leon Moussa; Christopher Siatskas; Rebecca Lim; Euan M Wallace; Graham Jenkin; Claude C A Bernard
Journal:  J Neuroinflammation       Date:  2015-06-03       Impact factor: 8.322

Review 7.  Is multiple sclerosis a mitochondrial disease?

Authors:  Peizhong Mao; P Hemachandra Reddy
Journal:  Biochim Biophys Acta       Date:  2009-07-14
  7 in total

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