Literature DB >> 12388481

Clinical comparison of standard-dose and 50% reduced-dose abdominal CT: effect on image quality.

Mannudeep K Kalra1, Srinivasa Prasad, Sanjay Saini, Michael A Blake, Jose Varghese, Elkan F Halpern, James H Thrall, James T Rhea.   

Abstract

OBJECTIVE: We hypothesized that radiation doses for abdominal CT could be reduced by adjusting the dose for a patient's weight and cross-sectional abdominal dimensions, with the resultant scans still being of diagnostic quality. SUBJECTS AND METHODS: Using a multidetector CT scanner, we prospectively studied 39 patients who were 65 years and older who had a known history of cancer. After performing a diagnostic contrast-enhanced CT examination, we obtained four slices each (centered at the top of the right kidney) at a standard radiation dose (240-300 mA) and at a 50% reduced dose (120-150 mA) at a constant kilovoltage of 140. Scans were obtained during a single breath-hold, with a 2.5-mm detector configuration and a slice pitch of 6:1. Reconstructed slice thickness was 5 mm. In a blinded review, two radiologists rated the randomized CT scans for overall image quality and anatomic details of liver, spleen, adrenal glands, kidneys, pancreas, and abdominal wall, using a 5-point scale (1 = unacceptable, 2 = substandard, 3 = acceptable, 4 = above average, and 5 = superior). Patients' weight and abdominal circumference, area, and anteroposterior and transverse diameters were correlated with image quality of scans obtained at standard-dose and 50% reduced-dose CT. Statistical analysis of the data was performed using Wilcoxon's signed rank test.
RESULTS: Overall, the image quality score was significantly higher (p < 0.005) on the scans obtained with standard-dose CT. No statistically significant difference in image quality was noted in the 50% reduced- and standard-dose CT scans in patients who weighed less than 180 lb, or 81 kg, (p > 0.05) and who had a transverse abdominal diameter of less than 34.5 cm (p > 0.05), an anteroposterior diameter of less than 28 cm (p > 0.05), a cross-sectional circumference of less than 105 cm (p > 0.05), and a cross-sectional area of less than 800 cm(2) (p > 0.05). Good interobserver agreement (p > 0.5) was found between the two reviewing radiologists.
CONCLUSION: Abdominal CT scan quality appears to be acceptable even with a 50% reduction in radiation dose except in patients with large anthropometric measurements. A reduction in CT radiation dose is possible if the tube current is optimized for the patient's weight and abdominal dimensions.

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Year:  2002        PMID: 12388481     DOI: 10.2214/ajr.179.5.1791101

Source DB:  PubMed          Journal:  AJR Am J Roentgenol        ISSN: 0361-803X            Impact factor:   3.959


  29 in total

1.  Management of patient dose and image noise in routine pediatric CT abdominal examinations.

Authors:  Francis R Verdun; D Lepori; Pascal Monnin; Jean-François Valley; Pierre Schnyder; F Gudinchet
Journal:  Eur Radiol       Date:  2004-01-13       Impact factor: 5.315

Review 2.  PET/CT: a new imaging technology in nuclear medicine.

Authors:  Heiko Schöder; Yusuf E Erdi; Steven M Larson; Henry W D Yeung
Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-09-05       Impact factor: 9.236

3.  Comparison of image quality between conventional and low-dose nonenhanced head CT.

Authors:  Mark E Mullins; Michael H Lev; Peter Bove; Cara E O'Reilly; Sanjay Saini; James T Rhea; James H Thrall; George J Hunter; Leena M Hamberg; R Gilberto Gonzalez
Journal:  AJNR Am J Neuroradiol       Date:  2004-04       Impact factor: 3.825

Review 4.  Optimizing technique for multi-slice CT.

Authors:  Sanjay Saini; Roy V Dsouza
Journal:  Eur Radiol       Date:  2003-12       Impact factor: 5.315

Review 5.  Multislice CT: update on radiation and screening.

Authors:  Mannudeep K Kalra; Michael M Maher; Sanjay Saini
Journal:  Eur Radiol       Date:  2003-12       Impact factor: 5.315

6.  Use of 100 kV versus 120 kV in computed tomography pulmonary angiography in the detection of pulmonary embolism: effect on radiation dose and image quality.

Authors:  Maninderpal Kaur Gill; Anushya Vijayananthan; Gnana Kumar; Kasthoori Jayarani; Kwan-Hoong Ng; Zhonghua Sun
Journal:  Quant Imaging Med Surg       Date:  2015-08

7.  Low Dose MDCT with Tube Current Modulation: Role in Detection of Urolithiasis and Patient Effective Dose Reduction.

Authors:  Prakashini Koteshwar; Chandan Kakkar; Smiti Sripathi; Anushri Parakh; Rajendra Shrivastav
Journal:  J Clin Diagn Res       Date:  2016-05-01

Review 8.  Reducing radiation dose in emergency computed tomography with automatic exposure control techniques.

Authors:  Mannudeep K Kalra; Stefania M R Rizzo; Robert A Novelline
Journal:  Emerg Radiol       Date:  2005-05-12

9.  Optimization of Z-axis automatic exposure control for multidetector row CT evaluation of neck and comparison with fixed tube current technique for image quality and radiation dose.

Authors:  S Namasivayam; M K Kalra; K M Pottala; S M Waldrop; P A Hudgins
Journal:  AJNR Am J Neuroradiol       Date:  2006 Nov-Dec       Impact factor: 3.825

10.  Assessment of image quality of a standard and three dose-reducing protocols in adult cranial CT.

Authors:  Sadi Gündoğdu; Kamran Mahmutyazicioğlu; Hüseyin Ozdemir; Ahmet Savranlar; Kiyasettin Asil
Journal:  Eur Radiol       Date:  2004-12-02       Impact factor: 5.315

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