| Literature DB >> 12374931 |
I Wilmut1, N Beaujean, P A de Sousa, A Dinnyes, T J King, L A Paterson, D N Wells, L E Young.
Abstract
Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.Mesh:
Year: 2002 PMID: 12374931 DOI: 10.1038/nature01079
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962