Literature DB >> 12374931

Somatic cell nuclear transfer.

I Wilmut1, N Beaujean, P A de Sousa, A Dinnyes, T J King, L A Paterson, D N Wells, L E Young.   

Abstract

Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.

Mesh:

Year:  2002        PMID: 12374931     DOI: 10.1038/nature01079

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  93 in total

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