| Literature DB >> 12374341 |
Kung-Bin Sung1, Chen Liang, Michael Descour, Tom Collier, Michele Follen, Rebecca Richards-Kortum.
Abstract
We have built a fiber-optic confocal reflectance microscope capable of imaging human tissues in near real time. Miniaturization of the objective lens and the mechanical components for positioning and axially scanning the objective enables the device to be used in inner organs of the human body. The lateral resolution is 2 micrometers and axial resolution is 10 micrometers. Confocal images of fixed tissue biopsies and the human lip in vivo have been obtained at 15 frames/s without any fluorescent stains. Both cell morphology and tissue architecture can be appreciated from images obtained with this microscope.Entities:
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Year: 2002 PMID： 12374341 DOI： 10.1109/TBME.2002.803524
Source DB: PubMed Journal: IEEE Trans Biomed Eng ISSN： 0018-9294 Impact factor: 4.538