Literature DB >> 12361913

The immune response to infection with Treponema pallidum, the stealth pathogen.

Juan C Salazar1, Karsten R O Hazlett, Justin D Radolf.   

Abstract

Cutaneous immunobiology and spirochetal molecular biology have allowed investigators to propose a conceptual framework for the development of both the innate and adaptive immune response to Treponema pallidum infection. While some clinical manifestations can be attributed to humoral responses, most can be attributed to a combination of local innate and adaptive cellular immunity.

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Year:  2002        PMID： 12361913     DOI： 10.1016/s1286-4579(02)01638-6

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  40 in total

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2.  Ancient pathogens in museal dry bone specimens: analysis of paleocytology and aDNA.

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3.  Lipoprotein-dependent and -independent immune responses to spirochetal infection.

Authors:  Juan C Salazar; Constance D Pope; Meagan W Moore; Jonathan Pope; Thomas G Kiely; Justin D Radolf
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4.  A Homology Model Reveals Novel Structural Features and an Immunodominant Surface Loop/Opsonic Target in the Treponema pallidum BamA Ortholog TP_0326.

Authors:  Amit Luthra; Arvind Anand; Kelly L Hawley; Morgan LeDoyt; Carson J La Vake; Melissa J Caimano; Adriana R Cruz; Juan C Salazar; Justin D Radolf
Journal:  J Bacteriol       Date:  2015-03-30       Impact factor: 3.490

Review 5.  The Treponema pallidum Outer Membrane.

Authors:  Justin D Radolf; Sanjiv Kumar
Journal:  Curr Top Microbiol Immunol       Date:  2018       Impact factor: 4.291

6.  Structural and thermodynamic characterization of the interaction between two periplasmic Treponema pallidum lipoproteins that are components of a TPR-protein-associated TRAP transporter (TPAT).

Authors:  Chad A Brautigam; Ranjit K Deka; Peter Schuck; Diana R Tomchick; Michael V Norgard
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7.  Assessment of the kinetics of Treponema pallidum dissemination into blood and tissues in experimental syphilis by real-time quantitative PCR.

Authors:  Juan C Salazar; Asha Rathi; Nelson L Michael; Justin D Radolf; Linda L Jagodzinski
Journal:  Infect Immun       Date:  2007-04-16       Impact factor: 3.441

8.  Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL β-BARREL DOMAIN.

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Journal:  J Biol Chem       Date:  2015-03-24       Impact factor: 5.157

Review 9.  Outer membrane proteins of pathogenic spirochetes.

Authors:  Paul A Cullen; David A Haake; Ben Adler
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10.  Assessment of cell-surface exposure and vaccinogenic potentials of Treponema pallidum candidate outer membrane proteins.

Authors:  Farol L Tomson; Patrick G Conley; Michael V Norgard; Kayla E Hagman
Journal:  Microbes Infect       Date:  2007-06-03       Impact factor: 2.700
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